Volume 4, Issue 3 (12-2021)
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Sadeghifard N, zamirnasta M. Title: The study of frequency of oropharynx microbiome among healthy children under 6 years old in Ilam city during 2015. Journal title 2021; 4 (3)
URL: http://newresearch.medilam.ac.ir/article-1-1639-en.html
URL: http://newresearch.medilam.ac.ir/article-1-1639-en.html
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Abstract: (1126 Views)
Acute respiratory infection is one of the primary diseases that causes high morbidity and mortality in children, especially in developing countries, where 70% of deaths are in Africa and Southeast Asia (1). . The latest statistics show that approximately 150 million new cases of pneumonia are diagnosed worldwide each year, more than 90% of which occur in developing countries and 30% of annual deaths in children under 5 years of age. Is (2). In Iran, several studies have been performed on selected populations of children with acute respiratory infections in different parts of the country, which have yielded different results, so an accurate statistical picture of the extent and importance of acute respiratory infections is not available (3). . Acute respiratory infection is often caused by a new invasion or abnormal release (development) of a specific pathogen into the airway, which in addition to the host defense also affects the incidence and severity of infection (4). , Microbiome refers to the overall microbial community and its biomolecules in a defined environment (5). It describes the fundamental role of microbiome in human health (6).
Research based on culture studies and, more recently, culture-independent methods have identified a microbial community in the lower respiratory tract of a healthy individual. (7).
Therefore, studying and informing about the prevalence of bacteria and viruses in pediatric uropharynx and also better understanding of bacterial colonization and their interaction, can be effective in predicting changes in bacterial ecology and design control strategies (including interference in colonization) . In particular, determining the rate of asymptomatic colonization with potential pathogens is important to predict the spread of the disease in the community and to design strategies for prevention and treatment. Therefore, respiratory infections in both developing and developed countries have a heavy economic burden on the family and society. Finally, considering the importance of respiratory infections in our country, in this study we try to investigate the prevalence and frequency of oropharyngeal microbiome in children under 6 years of age in Ilam by culture method and its relationship with the underlying variables to be evaluated. , And thus provide the necessary ground for further studies by researchers in the future
Research based on culture studies and, more recently, culture-independent methods have identified a microbial community in the lower respiratory tract of a healthy individual. (7).
Therefore, studying and informing about the prevalence of bacteria and viruses in pediatric uropharynx and also better understanding of bacterial colonization and their interaction, can be effective in predicting changes in bacterial ecology and design control strategies (including interference in colonization) . In particular, determining the rate of asymptomatic colonization with potential pathogens is important to predict the spread of the disease in the community and to design strategies for prevention and treatment. Therefore, respiratory infections in both developing and developed countries have a heavy economic burden on the family and society. Finally, considering the importance of respiratory infections in our country, in this study we try to investigate the prevalence and frequency of oropharyngeal microbiome in children under 6 years of age in Ilam by culture method and its relationship with the underlying variables to be evaluated. , And thus provide the necessary ground for further studies by researchers in the future
: Cross sectional |
Received: 2021/10/2 | Accepted: 2021/12/1 | Published: 2021/12/1
Received: 2021/10/2 | Accepted: 2021/12/1 | Published: 2021/12/1
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