1 723 General Moayeri Ardeshir b Mohamadpour Shahram c b Department of Anatomical Sciences, School of Medicine, Ilam University of Medical sciences, Ilam, Iran c Department of Anatomical Sciences, School of Medicine, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 21 04 2015 16 06 2015
719 General Production of the product from the combination of Arnbia euchroma plant and van gum Sharifi Ali d Abbasi Naser e d Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran e Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 23 10 2015 09 12 2015 722 General Ultrasonic-assisted green liquid extraction micro-extraction method based on solvent-based polymer nanoparticles for kinematic, ferulic, gallic acid and rutin measurements in olive, almond and sesame oil samples by HPLC-UV Basati Gholam f Shiri Sabah f Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 21 12 2016 11 03 2017 Abstrac A novel, simple, sensitive and green ultrasonic-assisted liquid–liquid microextraction method based on a synthetic citric acid–glycerol nanopolymer solution was used for the extraction of antioxidant acids (ferulic, cinnamic, gallic acid and rutin) in five kinds of oil samples from vegetables. The synthetic nanopolymer from citric acid and glycerol with absolute molar ratio was synthesized, and its specifications were characterized by (FTIR, DLS, GPC, AFM and NMR). Its solution as a green extractor for oil samples was added to n-hexane containing analytes. Then, the extraction was speeded up by using ultrasonic. After the extraction, phase separation (rich phase/n-hexane phase) was accomplished by using a centrifugation. Rich phase in lower phase was removed by a micro-syringe and injected to reverse-phase HPLC with UV detector. Volume of nanopolymer solution, concentration of nanopolymer, extraction time and temperature of ultrasonic bath were optimum conditions and obtained by response surface methodology. This method has good linear calibration ranges between 0.7 and 1300 μg L−1, coefficients of determination (r2 > 0.9831) and low limits of detection between 0.05 and 0.81 μg L−1. This method was successfully used to determine target analytes in oil samples of olive, almond, sesame, hazelnut and edible with satisfactory inter–intraday precision and recoveries (93t.4–107.1%).. 715 General Epidemiological Study on Injuries in Ilam from 2010 to 2017 Shafiei Elham h Nademi Arash h Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 23 08 2017 03 10 2017 خلاصه ضرورت اجرای طرح:   سوانح یکی از عمده ترین همه گیری های بیماریهای غیر واگیر در قرن حاضر را تشکیل میدهد و به عنوان اتفاقی  و تصادفی محسوب نمی شوند، بلکه بخشی از بهایی است که انسان به ازاء پیشرفت تکنولوژی می پردازد(1-3). سوانح و حوادث از دیرباز به عنوان یک عامل مخرب و مرگ زا برای انسان شناخته شده است(4).  براساس آمارهای منتشره ضایعات ناشی از حوادث یکی از پنج علت مرگ در گروه های مختلف سنی در کشورهای پیشرفته و درحال پیشرفت می باشد. همچنین هزینه و مخارج ناشی از حوادث بسیار سرسام آور بوده و گذشته از ان سالانه میلیون ها نفر در اثر جراحات ناشی از حوادث دچار انواع معلولیت ها می شوند که این امر باعث از دست رفتن نیروی انسانی فعال به همراه میلیون ها ساعت کار مفید می گردد(5-7). حادثه یک واقعه پیش بینی نشده توسط فرد است که نتیجه اش ضررو زیان قابل تشخیص می باشد و به عبارت دیگر حادثه واقعه ای است غیر منتظره که به وسیله انسان بوجود می آید و نتیجه آن ایجاد آسیب قابل تشخیص است(8). امروزه حوادث به عنوان یک مشکل همه گیر نه تنها درجاده بلکه در خانه، مدرسه، مراکز تفریحی، میادین ورزشی و کارگاه ها مطرح و یکی از معضلات مهم کشورهای صنعتی و در حال توسعه می باشد(9). از این رو حوادث در همه جا خطراتی مانند نقص عضو، ناتوانی، مرگ خصوصا برای کودکان و نوجوانان را در برمیگیرد که بدون برنامه ریزی جدی و کاربردی ممکن است رسیدن به بهداشت و سلامت برای همگان را به مخاطره بیندازد. یکی از مسائل تهدیگر سلامتی در جوامع  کنونی تروماها می باشد. در سال 2000 تروما باعث مرگ ومیر  بیش از 6 میلیون نفر در جهان شده است که حدود 63 درصد از این مرگ ها به علت آسیب های غیر عمدی رخ داده است(10).بالا بودن میزان مرگ ومیر ناشی از سوانح موجب شده تا کشورهای مختلف با مطالعه  ویژگیهای جمعینی به شناسایی علل وزمینه های  بروز حوادث وتدوین پیش گیرانه بپردازد.در ایران یک نظام ملی ثبت تروما وجود ندارد.وقتی ما اطلاعات درستی از چگونگی بروز سوانح نداریم، قطعا نمی توانیم برنامه ریزی درستی جهت پیشگیری ویا درمان عوارض ناشی از آن داشته باشیم.با توجه به نامشخص بودن وضعیت چگونگی بروز سوانح مختلف ودر دسترس نبودن مطالعه ای در این زمینه ، نیاز به مطالعه ای جامع دراین راستا احساس می شود. در صورت تعیین وضعیت وماهیت سوانح در شهر ایلام می توان برنامه ریزی وطراحی راه کارهای مناسب از این گونه حوادث پیشگیری نموده، یا از عوارض احتمالی آنها کاست.[a1]      714 General Comparison of the effectiveness of rosuvastatin and atorvastatin on changes in LDL, triglyceride and HDL by systematic review and meta-analysis Tavan Hamed j Qavam Samiramis k Sayehmiri Kourosh l j Ilam University of Medical Sciences, Ilam, Iran k Department of Cardiology, School of Medicine, Ilam University of Medical sciences, Ilam, Iran l Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 22 12 2017 22 01 2018 Among cardiovascular diseases, Coronary Artery Disease (CAD) accounts for a large proportion of deaths and disabilities due to cardiovascular disease. Pharmacological, interventional and surgical methods are used to treat coronary artery stenosis (1, 2). One of the methods that has been used in recent years to reduce myocardial necrosis during PCI is the use of statin drugs, especially atorvastatin and rosuvastatin (3, 4). Some experimental studies have shown that the use of atorvastatin reduces myocardial infarction (MI) around non-emergency PCIs (5, 6). On the other hand, a small number of studies have shown that the use of high doses of atorvastatin A single dose of 80 mg or rosvastatin 40 mg one day before PCI also reduced infarction around PCI (7, 8). 721 General Seroprevalence of Toxoplasma gondii in women of child–bearing age referred to clinical laboratories in Ilam, western Iran Azami Milad m m Ilam University of Medical Sciences, Ilam, Iran 1 11 2019 2 3 0 0 26 05 2018 25 06 2018 Background: Primary infection with toxoplasmosis during pregnancy can be transmitted to the fetus and may cause serious complications. Considering the importance of toxoplasmosis, the present study was conducted to determine the seroprevalence of toxoplasma gondii (T.gondii) toxoplasmosis in women of child-bearing age in Ilam. Methods: This cross-sectional study was conducted during April 2015 and March 2017, on women of child-bearing age (15-49 years old) that referred to laboratories in Ilam. Sampling was done based on census. Five milliliter venous blood was collected from each participant and the samples were examined using ELISA method. Statistical analysis was performed using SPSS ver. 17. In the analytical statistics, Kruskal-Wallis and Mann-Whitney tests were used. Results: A total 797 women of child-bearing age with mean age of 29.92 ± 7.23 years were examined in this study. The total seroprevalence of T. gondii was 23.46% (187 cases). The seroprevalence of IgG and IgM antibodies against T. gondii was 23.4% and 0.6%, respectively. The relationship between seroprevalence of IgM antibody and age (P= 0.37), level of education (P= 0.501), occupation (P= 0.20), and residence (P= 0.761) were not significant. The relationship between seroprevalence of IgG antibody and level of education (P= 0.196), occupation (P= 0.711), and residence (P= 0.101) were not significant but it was significantly associated with age (P< 0.001).     Conclusion: The results of this study showed that the seroprevalence of IgG antibody against T. gondii is 23.7%, which is relatively high. Prenatal screening can help to identify susceptible women to T. gondii. 727 General Investigating the effect of Crocus sativus L. petal hydroalcoholic extract on inflammatory and enzymatic indices resulting from alcohol use in kidney and liver of male rats Azizi Monireh n Amraei Mansour Bakhtiyari Salar p n Department of Anatomical Sciences, School of Medicine, Ilam University of Medical sciences, Ilam, Iran p Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 22 05 2018 25 07 2018 Background: Studies have shown that consumption of high levels of alcohol causes many negative effects on the liver and kidneys where antioxidant ingredients can be a proper solution to reducing the resulting damages. So, the present study investigated the effect of hydroalcoholic extract of Crocus sativus L. (saffron) petal with antioxidant properties on the changes in inflammatory and enzymatic indices resulting from alcohol use in the male rats’ kidney and liver. Materials and methods: After preparing the extract, LD50 was determined and highperformance liquid chromatography (HPLC) was employed to specify the type and the rate of the active ingredients of the extract. Then, 36 male Wistar rats were randomly assigned into six groups (n=6). The first group was only administered with normal saline and the second group only received ethyl alcohol 6 mL/kg/day·BW. The third and the fourth groups received ethyl alcohol 6 mL/kg/day·BW plus 167.5 and 335 mg/kg/day·BW saffron petal extract for 8 weeks. The fifth and the sixth groups received ethyl alcohol 6 mL/kg/day·BW for the first 8 weeks and were subsequently gavage fed on saffron extract for 167.5 and 335 mg/kg/day·BW, respectively, during the next 8 weeks. In the beginning and after the termination of the treatment, blood samples were collected from all rats. Results: The LD50 of the extract was about 670 mg/kg. The HPLC results indicated that the extract contains important antioxidant ingredients. At the end of the study, the serum concentration of the inflammatory indices, renal enzymes, and hepatic enzymes experienced a significant reduction in all of the intervened groups compared to the negative control group (minimum significant difference: P<0.05) except for the treatment group 1. Conclusion: Based on the current results, the extract has a protective effect in a dosagedependent way and greater protective roles were documented 720 General The Study of the Effectiveness of a Mixture of Arnebia Euochroma and Gum Extract in Animal Oils and Comparing It with Honey in Diabetic Foot Ulcer Sharifi Ali Abbasi Naser Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 23 07 2018 27 10 2018 One of the most important causes of disability in diabetic patients is diabetic foot ulcers. Native use of medicinal herbs may significantly affect the wound healing process. In this study, a mixture of Arnebia euochroma extracts and essential oil of Pistacia Atlantica in animal oil used for healing diabetic wounds was compared with natural honey. Thirty male Wistar rats weighing 250 g became diabetic. Wounds of equal size were created in their back area and the wound was dressed with a mixture of Arnebia euochroma and essential oil of Pistacia Atlantica in animal oil. Afterward, their recovery process was photographed daily. Finally, when we saw evidence of rats' wound healing; we killed rats and searched tissue granulation and epithelialization process. The study results showed that Arnebia euochroma and gum mixture at a concentration of 5% of animal oils was more effective compared to honey. Local and regional experiences can be a good source to access pharmaceutical products and services for patients, a scientific reason for this study. We found a more effective ointment for wound dressing. It can help diabetic patients. The oral forms of these plants are recommended to be provided. 718 General Comparison of the Effects of Oral Arnebia Euchroma and Oral ANGIPARS on Wounds in Diabetic Rats Sharifi Ali Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 23 09 2018 27 10 2018 Diabetic foot ulcer is one of the most common causes of amputation and imposes high social costs. The present study was conducted to evaluate the effect of oral arnebia euchroma extract on wounds in diabetic rats and was compared with oral and topical forms of ANGIPARS.Thirty diabetic male Wistar rats were categorized into different groups with similar wounds, and were treated with oral and topical forms of arnebia euchroma extract and ANGIPARS ointment and capsules, and were compared with each other and the control group. The clinical and statistical results indicate the superior effect of oral and topical forms of arnebia euchroma extract in comparison with oral and topical forms of ANGIPARS.The epithelial thickness(F (4.25) = 4189.10, p<0.01) and complete healing time(F (4.25) = 18.01, p<0.01), were respectively calculated. It is recommended that a human study be conducted to determine the level of blood glucose and its effect on TNFa and myeloperoxidase as the factors affecting tissue repair 712 General Biochemical parameters of rickets in iranian children: a systematic review and meta analysis Tavan Hamed Shohani Masoumeh Kalvandi Gholamreza Ilam University of Medical Sciences, Ilam, Iran Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 22 11 2018 20 01 2019 Rickets or osteoporosis is a bone disease that occurs in infants and children (1-2). In this disease, the baby's bones become soft for a number of reasons. Ricketts cause bone loss and bone growth and increase the risk of bone fractures. The main cause of rickets is vitamin D deficiency, but calcium deficiency is also effective .Numerous studies have been conducted on the causes and symptoms of Rashidism in the world. In order to confirm the results of these studies, a meta-analysis study is necessary. The aim of this study was to determine the causes and symptoms of rickets in Iran and to determine this level in terms of mineral deficiency in the body (Ca, Alk and PO4), age, sex and weight of patients, risk factors through systematic review and meta-analysis. 716 General Epidemiology of self-immolation in iran:systematic review and meta-analysis Tavan Hamed Valizadeh Reza Sayehmiri Kourosh Shohani Masoumeh Ilam University of Medical Sciences, Ilam, Iran Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 21 01 2019 27 02 2019 Suicide methods vary in different countries based on culture, symbols, symbols and religion. Successful suicide means gaining his soul and if it leads to death. Suicide is one of the social psychological problems and makes it angry (suicide is common in the age group of 15 to 44 years and is the fourth leading cause of death and the sixth leading cause of disability in the world. Since there are no accurate statistics on the causes of self-immolation in Iran and the incidence of it varies in different regions, so understanding these factors can make it necessary for the medical community in planning for financial reduction. According to numerous studies on types of self-immolation in Iran and in order to confirm the results of these studies, a meta-analysis study is necessary to be accurate and valid is the level of planners and researchers in this field. The aim of this study was to investigate the causes of self-immolation in Iran through systematic review and meta-analysis methods. 713 General Investigating the Causes of trauma and Its risk factors in iran:a systematic review and meta-analysis Tavan Hamed Sayehmiri Kourosh Ilam University of Medical Sciences, Ilam, Iran Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran 1 11 2019 2 3 0 0 05 01 2019 27 02 2019 Trauma is one of the leading causes of death and disability in different societies (1). Worldwide, 1.2 million people die each year in road accidents and about 50 million are injured. These figures are projected to increase by about 65% over the next 20 years (1-2). It is estimated that for every death resulting from injuries, 16 cases result in hospitalization and 400 cases require outpatient services or with limited transient activity (2). Accidents are the leading cause of death in trauma (3). In Iran, trauma is one of the most common causes of death (5, 4). Every year, more than 5 million people around the world die from an accident (570 people per hour). In developing countries, trauma is the leading cause of death in adolescents, as well as the cause of disability and economic damage related to the health of these countries (6). Trauma can be divided according to the location of injury such as head trauma, abdominal trauma, etc. Or based on the characteristics of the causative agent of the trauma, such as penetrating abdominal trauma (for example, with a sharp object) or blunt trauma, as well as thermal or compressive trauma (barotrauma), etc. (7). Impenetrable trauma, slow trauma to physical injury. A part of the body indicates that it may have been caused by an accident or physical blow. The term usually refers to traumatic injury. In addition, bruising is the first type of more advanced injury, such as bruises, abrasions, wounds, and bone fractures. Impact injury is different from incision; Injury in which something like a bullet enters the body (8).