Technology and Research Information System 4 4 2022 3 1 The study of clostridium difficile strains colonization in hospitalized children in Imam Khomaini hospital- Ilam- Iran 0 0 FA Nourkhoda Sadeghifard Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran Sobhan Ghafourian Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran mahshad sayadi Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran یکی از شایع ترین عوارض بستری شدن در بیمارستان، ابتلا به اسهال بیمارستانی است(1). از مهم ترین عوامل شایع اسهال بیمارستانی، کلستریدیوم دیفیسیل بوده که ایجاد کننده ی اسهال مرتبط با آنتی بیوتیک است . بیماری هایی که این باکتری ایجاد می کند پیامد هایی از جمله افزایش مدت زمان بستری و هزینه را در پی دارد(2). از عوامل زمینه ساز در ایجاد عفونت کلستریدیوم دیفیسیل می توان به استفاده بی رویه از آنتی بیوتیک ها وتغییر میکروبیوم روده ، استفاده از داروهای ضد رفلکس در کودکان، بستری طولانی مدت در بخش های مراقبت ویژه ، بیماری های زمینه ای، محیط و پرسنل بیمارستان اشاره نمود(3). سالانه تعداد زیادی از کودکان به اسهال بیمارستانی ناشی ازکلستریدیوم دیفیسیل مبتلا می شوند و با افزایش مقاومت های آنتی بیوتیکی جهت درمان این عفونت و احتمال عود بیماری و نبود اطلاعات کافی در زمینه ی میزان کلونیزاسیون این عفونت در کودکان ،و عدم روش های مناسب تشخیص در ایران ،بررسی وجود این باکتری به خصوص در کودکان از اهمیت بالایی برخوردار است.در ایلام هیچ اطلاعاتی در زمینه میزان کلونیزاسیون این باکتری وجود ندارد و از طرفی بر اساس مقالات انجام شده بسیاری از کودکان این باکتری را حمل نموده و نوع توکسین زای آن از اهمیت بیشتری در جهت پیشرفت به بیماری کولیت برخوردار است ،لذا در این تحقیق برآن شدیم که میزان کلونیزاسیون کلستریدیوم دیفیسیل در کودکان بستری دربیمارستان امام خمینی شهر ایلام راانجام داده تا اطلاعاتی دراین زمینه در اختیار کادر درمانی بیمارستان ها قرار گرفته و از طرفی بررسی ریبوتایپ های مختلف نمونه های جدا شده می تواند کمک شایانی در کنترل انتشار این باکتری و بیماری ناشی از آن داشته باشد.

Technology and Research Information System 4 4 2022 3 1 Phenylketonuria Screening in Iranian Newborn: A Systematic Review and Meta-Analysis 0 0 FA Mehdi Shokri Department of Pediatrics, School of Medicine, Ilam University of Medical sciences, Ilam, Iran Milad Azami Ilam University of Medical Sciences, Ilam, Iran Hadis Zamanifar Ahvaz Jundishapour University of Medical Sciences Fatemeh Kazemi Qazvin University of Medical Sciences Parviz Karimi Department of Pediatrics, School of Medicine, Ilam University of Medical sciences, Ilam, Iran Gholamreza Badfar Background Phenylketonuria (PKU), which is characterized by a deficiency of phenylalanine hydroxylase activity, is an autosomal recessive disorder of phenylalanine (Phe) metabolism. Newborn screening is the main population-based public health screening program that allows successful identification and treatment of PKU with low-Phe diet. The aim of this study was to evaluate the epidemiology of PKU screening in Iranian newborns. Methods The present study was designed based on MOOSE protocol and reporting was done in accordance with the PRISMA guidelines. The protocol of this systematic review was published in PROSPERO before it was performed (CRD42020162626). A comprehensive search was done in 10/10/2019 to find related literature on international online databases Web of Science, Scopus, EMBASE, Science Direct, PubMed/Medline, EBSCO, CINAHL, Cochrane Library, national online databases and the Google Scholar search engine. Heterogeneity among studies was assessed by I2 index and Q test. All meta-analyses were performed using Comprehensive Meta-Analysis Software ver. 2. P < 0.05 was considered significant.

Technology and Research Information System 4 4 2022 3 1 Application of Needle Trap Technique Using Functionalized Organic-Metal Framework for Determination of Organochlorine Pesticides in Air 0 0 FA Shiva Soury Alimohammad Abbasi Department of Occupational Health, School of Health, Ilam University of Medical sciences, Ilam, Iran Hojatollah Kakaei Department of Occupational Health, School of Health, Ilam University of Medical sciences, Ilam, Iran

Technology and Research Information System 4 4 2022 3 1 The Relationship between Metabolic Syndrome and Erosive Esophagitis: A Systematic Review and Meta-Analysis Study 0 0 FA Milad Azami Ilam University of Medical Sciences, Ilam, Iran Mohammad Karimian Department of Surgery, School of Medicine, Ilam University of Medical sciences, Ilam, Iran Majid Salamati Department of Surgery, School of Medicine, Ilam University of Medical sciences, Ilam, Iran Background The relationship between metabolic syndrome (MetS) and Barrett’s esophagus (BE) is still a challenging issue, and inconsistent results have been reported in different studies. Therefore, this study was conducted to determine the relationship between MetS and BE. Methods In this study, we followed the MOOSE protocol and results were reported according to the PRISMA guidelines. All study steps were performed independently by two authors. If necessary, the dispute was resolved by consultation with a third author. The search strategy is designed to find published studies. Comprehensive search was done in the following databases until July 2019: Cochrane Library, PubMed/Medline, Web of Science, Science Direct, EMBASE, Scopus, CINAHL, EBSCO, and Google Scholar search engine. All analyses were performed using Comprehensive Meta-Analysis Software Ver.2, while p-value lower than 0.05 was considered significant.

Technology and Research Information System 4 4 2022 3 1 Investigation and Identification of Chemical and pharmacologic Compounds of Thymbra spicata and Satureja khuzestanica Ilam by HS-SPME and GC-MS 0 0 FA maryam shahmohammadi medical school Hori Ghanei Alvar Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran Mahmoud Bahmani Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran Naser Abbasi Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran اسانس های روغنی ترکیبات معطری هستند که به طور وسیعی در صنایع عطر سازی، دارویی و غذایی مورد استفاده قرار می گیرند. قبل از شناسایی و استفاده از روغن های اسانسی، باید آنها را به طریقی از بسترشان خارج نمود. برای استخراج اسانس ها و عصاره ها روش های متعددی وجود دارد. این روش ها شامل تقطیر، فشار یا خراش یا تیغ زدن، روش HS-SPME، استخراج با حلال، استخراج به وسیله ی آنزیم های هیدرولیزکننده و استخراج به وسیله ی دی اکسید کربن می باشد. هدف از انجام این مطالعه، بررسی میزان مواد موثره اسانسی گیاهان دارویی مرزه خوزستانی و آویشن زوفایی به روش HS-SPME و GC-MS می باشد تا با شناخت ترکیبات اصلی و موثره گیاهان بتوانیم راحت تر به سمت تولید داروهای گیاهی موثر قدم برداریم.

Technology and Research Information System 4 4 2022 3 1 Evaluating of Risk Factors Affecting Social injuries in dormitory students of state universities of Ilam in 2015 0 0 FA fariba nazarpour university health ilam khosro shirini amuzesh va parvaresh Introduction: Any kind of behavior or practice that conflicts with the values ​​and norms accepted by the community is known as social harm, which can disrupt the function of the individual, the family and the community. The aim of this study was to investigate the social injuries of dormitory students and its effective factors among dormitory students. Materials & Methods: This descriptive-analytic study was carried out on 337 dormitory students of public universities in Ilam. A researcher-made questionnaire (69 items) was used to collect data. To evaluate the validity of the instrument from face validity, the relative content validity coefficient (CVR), Content validity index (CVI) was used. In this study, the CVI value was 0.85 and CVR was 0.76. The reliability of the questionnaire was assessed by Cronbach's alpha coefficient, which was 0.87. Data were analyzed using SPSS software version 20 and descriptive statistics were used to describe the data. Inferential statistics were used to analyze the data. Findings: Chi-square test showed a significant difference between the damage of illegitimate relationships with students' gender (p<0.05). There was a significant relationship between the status variables of friends, the lack of familiarity with living skills, lack of academic and educational facilities in dormitories and the occurrence of social injuries in the study population (p <0.05). Discussion & Conclusion: In this study, having family problems, history of depression, existence of peer group and friends and distant students from family safe environment were introduced as the most important factors affecting social harm in students. Therefore, it is suggested that to develop appropriate strategies, increase cultural and recreational programs in order to prevent Social harm.

Technology and Research Information System 4 4 2022 3 1 study of relationship between persister cells and vancomycin resistant biofilm of Enterococcus faecalis 0 0 FA Iraj Pakzad Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran vahab Hassan kaviar department of medical microbiology Sobhan Ghafourian Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran Abbas Maleki Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran Biofilm as a major cause of infection recurrence as well as chronic infections in many diseases including chronic urinary tract infections, cystic fibrosis, gingivitis, recurrent tonsillitis, surgical wound infections, middle ear infections in children and also leading Unfortunately, biofilms are responsible for causing a variety of antibiotic resistance and causing major problems in the treatment of diseases. Bacterial film-forming bacteria create antibiotic resistance by creating an extracellular matrix, and also by evading immune system agents by this mechanism. Enterococci are opportunistic bacteria that are resistant to a wide range of antibiotics and in some cases cause multiple resistance to antimicrobial agents and are important causes of nosocomial infections and also cause many diseases including Urinary tract infections, wound infections, skin and soft tissue infections, as well as bloodstream infections.Unfortunately, the increase in antibiotic resistance has led to impaired treatment of many diseases. Numerous experiments have shown that single cells (planktonic) are sensitive to antibiotics, but the formation of biofilms leads to resistance of these bacteria to antibiotics. So far, the cause of this phenomenon has been considered to be the protection of extracellular matrix layers around bacteria, which prevents the penetration and spread of antimicrobial agents, and this has led to extensive research on biofilms and other mechanisms that destroy them. However, various studies have now shown the role of persister cells in chronic infections, as well as the presence of these biofilm-resistant cells, suggesting that they may be the cause of these antibiotic tolerance in biofilms. These are the persisters, and the biofilm may play a lesser role. Finally, these studies can hypothesize that perhaps the main reason for the development of antibiotic tolerance in the biofilm of persister cells and the role of biofilm in antibiotic tolerance is ruled out. Therefore, in this study, various methods will be used to examine persister cells in antibiotic-tolerant biofilms, so that perhaps the reason for antibiotic resistance in persister cell biofilms will be introduced.

Technology and Research Information System 4 4 2022 3 1 The relationship between Body image and quality of life in pregnant women referring to health centers in Ilam province year in 2017 0 0 FA Zaynab Rezaeefard Arman Azadi Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran Yousef Veisani Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran Pregnancy is a unique experience that the transmission period can be accompanied by important physical, mental and social changes. Over the pregnancy, underlying alterations is established in appearance, BMI and body image, which can affect pregnant women’s quality of life. Body image is a multidimensional construct encompassing perceptions, attitudes, beliefs, feelings, and behaviors regarding onechr('39')s appearance and also is an essential aspect of mental health that a mistake perception from body image can lead to mental and physical problems. Organic, hormonal and psychological changes along with factors such as economic status, stressful events and body image disturbance can change one’s ability for doing the usual roles of life during pregnancy, affecting both maternal and infant health. QOL is a multidimensional dynamic concept, affecting the performance of individuals in physical, psychological, social and spiritual dimensions. This was a cross-sectional study conducted on 250 pregnant women attending health centers in a western city of Iran. Participants were selected using a random sampling method. Data collection tools comprised a sociodemographic questionnaire, Body Image Concern Inventory (BICI), and quality of life questionnaire (Short Form-12). Data were analyzed using SPSS software version 22, with the significance level set at p < 0.05 for all analyses

Technology and Research Information System 4 4 2022 3 1 The study of Common enteropathogenic bacteria in children with diarrhea in Ilam city by multiplex PCR method 0 0 FA Nourkhoda Sadeghifard Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran Zahra Amanpour Ilam University of Medical Sciences Diarrhea is still a major threat to the young population in low- and middle-income countries (1) and is a leading cause of death in children (2). According to the WHO, after HIV, the second leading cause of death in children under 5 is diarrhea (1). In 2015, diarrhea accounted for 8% of all under-5 deaths worldwide (3), and is also a problem not only in health but also in the economy due to the frequent hospitalization of children (4). ). Laboratory diagnosis of gastroenteritis pathogens is mainly based on microscopy, culture and immunoassay (5, 6), but these methods are time consuming or sometimes insensitive (7) and the delivery time of these tests also varies, for example in Campylobacter species and Or Salmonella which can last for several days (5). In developing countries, the diagnosis of diarrheal infections generally relies on clinical signs, which usually do not lead to accurate identification of the pathogen causing the disease, and in the absence of specialized tests, infections are managed using an experimental antibiotic regimen. This is often associated with overuse of antibiotics and the spread of bacterial resistance (8), so the need for a rapid and reliable diagnostic method is felt. Molecular methods have high sensitivity and specificity and with the help of it, bacterial agents can be identified simultaneously and specifically (9). Multiplex PCR experiments in recent years have paved the way for the diagnosis of gastrointestinal diseases (10).  Multiplex PCR is a fast and accurate method for detecting fecal pathogens (11). This method has shown high sensitivity compared to conventional methods for detecting most pathogens (10). Multiplex PCR is better because of its many advantages, including: simultaneous detection of a wide range of pathogens, faster time, lower costs and higher efficiency, and this leads to the use of this diagnostic tool in epidemiological studies of diarrheal infections (12). ). Rapid and simultaneous amplification of several genes in one reaction is one of the goals pursued in Multiplex PCR. One of the features of this test, in addition to its speed and cost-effectiveness, is to minimize the possibility of contamination in the studied samples (13). Having information about the prevalence of common diarrhea pathogens can be effective in controlling and properly managing the disease among Iranian infants and children. Therefore, due to the lack of sufficient information about the role of common gastrointestinal pathogens in pediatric diarrhea in Ilam, as well as the lack of appropriate diagnostic methods, gastrointestinal diseases of children are always considered as major health problems. On the other hand, most physicians rely on clinical symptoms. Therefore, finding a suitable method and diagnosis that is also fast, can help doctors in treating children for gastrointestinal infections in Ilam. Therefore, by conducting this study, the prevalence of gastrointestinal bacteria in children in Ilam has been determined and a new perspective in helping treatment will be provided to physicians.

Technology and Research Information System 4 4 2022 3 1 Genetic analysis of Shigella flexneri isolated from diarrheal patients in Ahvaz city by pulsed field gel electrophoresis 0 0 FA Nourkhoda Sadeghifard Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran MARYAM KARKOUB Ilam University of Medical Sciences Diarrhea is the second leading cause of death in children worldwide. (1). More than 165 million cases of Shigella are reported each year, resulting in the death of 1.1 million people (3.5). The main route of transmission of shigellosis is from one person to another through the oral fecal tract (5). In this study, pulse field gel electrophoresis (PFGE) method is used to determine Shigella flexnery types. PFGE is one of the best methods used in typology and epidemiological studies in different regions, this method with high reproducibility and differentiation Which can be used for all human pathogens (19). PFGE is considered the gold standard for most bacteria due to its high differentiation power and is also one of the most important molecular methods for epidemiological studies and bacterial typing (18). Unfortunately, in Ahvaz, municipal sewage is discharged into the Karun River, which is the main source of drinking for the people of the region and irrigation of agricultural products. This issue pollutes the river water with various intestinal pathogens, including Shigella. Due to the ease of transmission of Shigella through oral fecal routes and low dose of bacterial pathogenicity, Karun River water pollution to municipal wastewater is a major risk for Shigella and in addition, the tropical climate of Ahvaz causes a critical outbreak of Shigella in the region. Be. In recent years, due to the arbitrary use of antibiotics, the prevalence of antibiotic-resistant Shigella species has increased. And finding the right way to control the infection seems vital. The purpose of typing studies on strains of a particular bacterium is to provide laboratory evidence for genetic association of strains isolated from patients. Typing information is needed to know how to control the spread of disease in the community. Due to our limited information about the common Shigella flexneri clones in Ahvaz and their relationship with the distribution of resistance genes in the region, we decided in a study on Shigella flexneri samples collected in different years to study the molecular epidemiology and identify clones. Common during different years in Ahvaz with PFGE method.

Technology and Research Information System 4 4 2022 3 1 Evaluation the views and job satisfaction of midwives in Ilam city in 2018 0 0 FA mona bahmane Ilam University of Medical Sciences nasrin rashan Ilam University of Medical Sciences Ashraf Direkvand Moghadam Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran In recent decades, the hours and intensity of people's working lives have increased due to the imbalance between work and personal life. Hence, it has raised concerns about its impact on employed people. The term work-life balance has been coined to reflect these concerns. To achieve work-life balance, there is a lot of documentation about its benefits for the individual, the workplace and the community. The imbalance between work and personal life has caused midwives and nurses to experience stress and burnout, which has negative effects on hiring and retaining the workforce.After defending the proposal and approving the ethics committee of the university with the conditions of keeping the subjects' secrets and obtaining informed consent from the research units and the final approval of the above plan in the university, a written letter of introduction will be obtained from Ilam University of Medical Sciences. And the deputy of treatment is provided. After the above steps, a sampling permit will be obtained from the relevant authorities.