Technology and Research Information System
4
3
2021
12
1
Prevalence and rank sources of stress, coping skills and general health of people over 18 years –Ilam city 2017
0
0
FA
Yousef
Veisani
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
Fathola
Mohamadian
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
Prevalence and rank sources of stress, coping skills and general health of people over 18 years –Ilam city 2017
Technology and Research Information System
4
3
2021
12
1
: extractin and determination Polycyclic aromatic hydrocarbons in water an food samples using ultrasound-assisted solvent extraction followed by dispersive liquid-liquid microextraction based on the solidification of floating drop followed by HPLC
0
0
FA
Gholam
Basati
Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran
Sabah
Shiri
Asad
Mirzaei
Zoonotic Diseases Research Center, Ilam University of Medical sciences, Ilam, Iran
Shahram
Lotfei
Technology and Research Information System
4
3
2021
12
1
Title: The Compilation of Career development pattern of the nurses in Iran based on Delphi technique.
0
0
FA
Zeynab
Rahimi
Mosayeb
Mozafari
Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran
Jamil
Sadeghifar
Department of Public Health and Health Education, School of Health, Ilam University of Medical sciences, Ilam, Iran
Sanaz
Azami
Department of Medical Education, Educational Development Center, Ilam University of Medical sciences, Ilam, Iran
ر فرد شاغلی مسیر شغلی را طی می کند که کارراهه نامیده می شود.برنامه ریزی و مدیریت این کارراهه به شیوه ای مناسب سبب خوشنودی از آن می شود.طراحی این مسیر پیشرفت سبب پیشرفت فرد در طی سنوات خدمت می گردد(1).
مبانی علمی طراحی و مدیریت مسیرهای ارتقا و تکامل شغلی بر مبناهای جدید در حال تحول و بازنگری است، به طوری که در طول دهه های گذشته، مدیریت و برنامه ریزی مسیرشغلی یکی از پیشرفته ترین مباحث مدیریت منابع انسانی بوده است.
براساس مطالعات انجام شده، افرادی که مسیر پیشرفت شغلی آنها با نیازهای تکاملی و ظرفیت هایشان متجانس است، تلاش افزون تری دارند تا دانش و مهارت خود را در طول کارراهه و مسیر ترقی و تکامل شغلی خود بهبود ببخشند(2).
از نظر شاین(Schein)یک حرفه از دیدگاه فرد، چندین مرحله ی عمده را پشت سر می گذاردکه این مراحل در طی سنوات خدمت در حال تکامل هستند؛ این مراحل شامل مراحل: رشد و اکتشاف، آموزش و پرورش، ورور به دنیای واقعی کار، آموزش های پایه ی اجتماعی شدن، عضویت در سازمان، عضویت دائمی در سازمان یا بحران میانه ی کاریا شروع مجدد، مقاومت کردن، آمادگی برای بازنشستگی یا انکار، و در نهایت بازنشستگی.
مراحل ذکر شده با مشخصات و ویژگی های خاص خود در واقع یک جدول زمانی داخلی را در ذهن هر کارمند ایجاد می کنند که وابسته به سن فرد نیستند بلکه وابسته به طی کردن مراحل شغلی و حرفه ای هستند.
تمامی پیشرفت ها و ارتقاهایی که در طول این سالیان می تواند هر کارمندی تجربه کند نیز بر طبق نظرشاین می تواند در سه پایه اندازه گیری گردد:رشد در توانایی ها و مهارت ها، حرکت به سمت بالا یا ارتقای رتبه ی شغلی در سلسله مراتب سازمانی، دستیابی به نفوذ و قدرت یا حس فرد در اینکه تا چه اندازه توانسته است در هسته ی داخلی یک سازمان نفوذ پیداکند(3).
براساس مراحلی که فرد شاغل در زمان خدمت خود پشت سر می گذارد باید نقشه راه و الگوی مشخصی وجود داشته باشد که فرد شاغل را در هر حرفه ای که هست راهنمایی کند و در واقع یک نقشه ی راه برای کارمندان باشد.که البته مفهوم کارراهه یا الگوی مسیر شغلی از دوجنبه قابل بررسی است: درونی وبیرونی؛ کارراهه بیرونی همان فرصت ها یا پیشینه های شغلی و محدودیت هایی است که از سوی شغل و سازمان مشخص شده است.اما کارراهه درونی در برگیرنده ی گرایش ها، ارزش ها، ادراکات و واکنش های مؤثر بر تجارب شغلی است که می تواند نتایج مهمی برای خشنودی، تعهد و باقی ماندن افراد دریک سازمان داشته باشد(2).
یکی از سازه های مهم در برنامه ریزی مسیر شغلی از لحاظ عوامل درونی جهت گیری کارراهه شغلی یا شناسایی تمایلات افراد برای انتخاب مسیرهای شغلی خود است(منبع سامان شیخی).جهت گیری شغلی برای شخص در سازمان عبارتست از خودپنداره ی فرد که از سه مقوله ی مهم تشکیل شده است: استعدادها و توانایی های ادراک خود-ارزش های اساسی از دیدگاه فرد- احساس تکامل یافته نسبت به انگیزه ها و نیازهایی که مربوط به مسیر شغلی می شود(4).
پژوهش های ادگار شاین در دهه ی 1970 نشان داد که خودپنداره ی تکامل یافته ی افراد در هشت مقوله یا لنگر شغلی منعکس می شوندکه عبارتند از استقلال و خودمختاری، امنیت و ثبات شغلی، شایستگی فنی و حرفه ای، شایستگی اداری و مدیریتی، خلاقیت و کارآفرینی، خدمت و از خودگذشتگی، چالش محض، سبک زندگی(4).
طبق تئوری شاین انتخاب های شغلی افراد تحت تاثیر تکامل و تثبیت لنگرهای شغلی قرار دارندکه شخص به رغم رویارویی با انتخاب ها و شرایط شغلی سخت؛تنها با وجود همسو بودن با لنگر شغلی ش منصرف و فرسوده نخواهد شد(2)
الگوهای شغلی دیگری همچون راجرRoger(2006)ویز و همکاران(2008)Wils & etal و چاپمن Chapman و بریستوBristowنیز وجود دارند که با بررسی الگوهای شغلی گفته شده به نظر می رسد اساس و مبنای بسط تمامی الگوها نمونه ی شاین است(2).
طبق ماده تبصره ی 46 آئین نامه تشکیلات و طبقه بندی مشاغل دانشگاه های علوم پزشکی؛ پرسنل پرستاری طی سالیان خدمت خود بر طبق مدرک تحصیلی و سنوات تجربی می توانند از قانون ارتقاء طبقه ی شغلی تا زمان بازنشستگی استفاده کنند(5).
علاوه بر این بر طبق سنوات تجربی، پرسنل می توانند رتبه های مقدماتی – پایه – ارشد – خبره و عالی را طی کنند؛ برطبق قانون ارتقای بهره وری بر طبق سابقه ی خدمت و کار در نوبت های کاری غیر متعارف به تناسب ساعت مؤظفی در هفته حداکثر تا 8 ساعت تقلیل می یابد(6).
قوانین حمایتی ذکر شده بر طبق ارتقا در رتبه و طبقه ی شغلی؛ سبب افزایش درآمد به صورت افزایش میزان حق شغل می شود، موارد ذکر شده در واقع عوامل بیرونی تاثیر گذار در مسیر شغلی هستند اما در واقع قوانین یا الگویی که بتواند سبب تقویت و هدایت کارراهه شغلی پرستاران با در نظر گرفتن عوامل درونی مؤثر در ارتقا و تکامل شغلی پرستاران باشد وجود ندارد.
به همین جهت موضوع مطالعه ی ما تدوین الگوی تکامل شغلی برای پرستاران در ایران است؛ تااینکه پرستاران بتوانند مسیر تکامل شغلی مشخصی را به صورت پله پله طی کنندکه در آن مسیر عوامل مؤثر و لنگرهای شغلی پرستاران در طی سنوات خدمت مدنظر قرار بگیرد.
Technology and Research Information System
4
3
2021
12
1
Survey of Workplace Violence against Nursing Students in Medical University of Ilam 2018
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0
FA
abdollah
normohammadi dehbalaee
ilam
ehsan
mohammadi
ilam
nastaran
afsordeh
ilam
Survey of Workplace Violence against Nursing Students in Medical University of Ilam 2018
Technology and Research Information System
4
3
2021
12
1
-survey effect cognitive intervention on reduce anexity patient intensive care unit
0
0
FA
Fatemeh
Ghiasi
Department of Anesthesiology, School of Allied Medical Sciences, Ilam University of Medical sciences, Ilam, Iran
Sara
Mohammadi
Department of Operating Room, School of Allied Medical Sciences, Ilam University of Medical sciences, Ilam, Iran
Technology and Research Information System
4
3
2021
12
1
Title: Investigation into the effectiveness of an Introduction to OSCE workshop in reducing the students of Ilam University of Medical Scinces ‘stress level during the test.
0
0
FA
Fatemeh
Ghiasi
Department of Anesthesiology, School of Allied Medical Sciences, Ilam University of Medical sciences, Ilam, Iran
The ASCII clinical trial is a method of assessment in which a student goes through different stations and is evaluated on a variety of topics. Each station includes a clinical program in which it interviews patients or includes an issue. It is the clinic where the volunteer is asked to interpret and solve it.
Each candidate's performance is marked by an evaluator in a structured checklist dedicated to that station. (1)
This test, like other assessment methods, has advantages and limitations; this method measures a wide range of skills. Measures cognitive goals, skills, and to some extent attitudes.
Its scoring is accurate and its feedback is instantaneous, but its disadvantages include high cost, time consuming and creating anxiety in the student. (2)
Studies show that ASCII test anxiety is largely related to test time, complexity, and techniques, as well as confusion about how to test. (3)
Due to the fact that one of the points of student anxiety is the student's unfamiliarity with how to hold this test, so we find that more solutions should be addressed in which the student is informed about the process of this test.
In a study conducted in Egypt to investigate the effect of ASCII test on nursing students, the student's previous experience of taking the ASCII test in the previous year affected the outcome of the study and caused two thirds of students to say that this method is appropriate. Has been and compared to other tests has created the least stress in them. (4) In a study conducted by Bagheri et al., This test was considered stressful, but this result was affected by not informing the students, the interval of one semester between the training of the course unit and the time of holding the test in Aski style. (5)
After these studies, we find that the more familiar students are with this test, the better their performance will be.
Evidence shows that in the clinical evaluation system of Iranian nursing and midwifery students, ASCII is a valid and reliable test and in order for students to perform better during the test, more detailed planning is needed before the test. (6)
A workshop is an organized set that provides opportunities for individuals to learn through thought, action, and discussion.
The term workshop ﺑﻪ ﺑﻪ ﺑﻪ ﺑﻪ ﺑﻪ. ﺑﻪ ﺑﻪ ﺑﻪ ﺑﻪ که که که که..........................
One of the workshops that will help people achieve their goals and achieve their goals. (7)
All of this reduces students' anxiety and greater preparation for the ASCII test.
Technology and Research Information System
4
3
2021
12
1
Investigation of the prevalence of SARS-CoV- 2 among hemodialysis patients in Ilam, Iran
0
0
FA
Azra
Kenarkoohi
Ilam University of Medical sciences, Ilam, Iran
Bahareh
Ghiasi
Department of Urology, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Elham
Bastani
Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
shahab
falahi
Ilam University of Medical Sciences, Ilam, Iran
Maryam
Maleki
Department of Physiology, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Technology and Research Information System
4
3
2021
12
1
Respecting for Human Dignity in Elderly nursing homes Residents in Elam in 2020
0
0
FA
farangis
akbari tahami
Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran
Masoumeh
Otaghi
Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran
Seyed Rahmatollah
Mousavimoghadam
Department of Islamic Education, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Arman
Azadi
Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran
Yousef
Veisani
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
سالمندی یک مسئله جهانی است و کشور ایران به عنوان کشوری باستانی با سابقه 2500 ساله از این قاعده مستثنی نیست(1). پدیده سالمندی آخرین دوره چرخه زندگی می باشد و طبق نظریه سازمان جهانی بهداشت سن 60 سال نقطه شروع سالمندی است(2) و در حال حاضر جمعیت سالمندی در جهان از 08/5 درصد در سال 1950 به 28/8 درصد در سال 2015 رسیده است در ایران سهم جمعیت بالای 65 سال از 4 به حدود 1/6 درصد رسیده است و تخمین زده اند که تا سال 2036 بیش از 11 درصد کل جمعیت سالمند باشند(22) و با افزایش بیماری های مزمن در این رده سنی، این گروه به مراقبت های بیشتری نیازمندند(1). نیازهای مراقبتی سالمندان فقط جنبه فیزیکی نیست بلکه تمام جنبه هااز جمله احساسات، حرکات، برداشت ها و شناخت ها را در برمی گیرد که همه این ها باید اخلاقی باشد(1).در واقع کرامت انسانی یک مفهوم مهم در قلب مراقبت های پرستاری است(3) و اساس و بنیاد مراقبت های پرستاری احترام به کرامت و منزلت افراد که خود دارای 5 مفهوم اصلی: احترام، حریم خصوصی، استقلال، حمایت و دادن اطلاعات لازم است، می باشد(4،5).
اولین بیانیه ای که در اعلامیه حقوق بشر در سال 1948 تصویب شده است به شناخت کرامت و حقوق برابر انسانی تاکید کرده است(6) و کرامت جزیی از حقوق اساسی بشر است و شامل استقلال، صداقت، عدالت و مسئولیت پذیری در برابر افراد است(7). هنگامی که شأن یک انسان رعایت می شود موجب کاهش استرس، افزایش اعتماد و رضایت آن فرد می شود(8) و از طرفی موجب احساس توانمندی و تصویر مثبت از خویش می گردد ودر صورت عدم رعایت آن موجب ایجاد افسردگی وعواقب غیر قابل کنترل آن می گردد(3). مطالعات بسیاری در رابطه با رعایت کرامت انسانی در سالمندان در محیط های بالینی و بیمارستان ها انجام شده است و کم تر به محیط هایی مانند سرای سالمندان توجه شده است و از طرفی سالمندان در سرای سالمندی باقی عمر خود را تا زمان مرگ می گذرانند و کم تر مورد توجه قرار می گیرند هدف از این مطالعه بررسی دیدگاه سالمندان، مراقبین و کارکنان سرای سالمندان و دانشجویان کارشناسی ارشد پرستاری سالمندی در رابطه با رعایت کرامت انسانی سالمندان می باشد.
Technology and Research Information System
4
3
2021
12
1
Title:Clinical and paraclinical manifestations and results of delivery in mothers with covid-19: A Case Series in Ilam
0
0
FA
Ashraf
Direkvand Moghadam
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
کروناویروس جدید 2019 (COVID-19) که از دسامبر 2019 از ووهان چین آغاز گردید، به عنوان بزرگترین تهدید اپیدمی است که جهان تاکنون با آن روبرو بوده است. از شروع این اپیدمی تا کنون، ویروس به 204 کشور یا سرزمین گسترش یافته و موجب ابتلاء 7 میلیون نفر گردیده است (4) به دلیل ظرفیت انتقال بالای این ویروس میزان عفونت ها و مرگ و میر ناشی از آن روزانه تغییر می کند (1). در نتیجه، سیستم های بهداشت و درمان با مشکلاتی از جمله مواجهه صحیح با افراد آلوده و افراد نیازمند به مراقبت جامع روبرو هستند(1). انتقال این ویروس از شخص آلوده به غیر آلوده بوسیله تماس قطرات تنفسی (سرفه یا عطسه) و لمس سطوح یا اشیاء توسط فرد آلوده صورت می گیرد(1).
برخی از مطالعات اخیر، نتایج بارداری در زنان مبتلاء به COVID-19 را مورد بررسی قرار داده و نتایج متفاوتی را ارئه نموده اند. در مطالعه chent و همکاران (2020) 9 نفر از زنان باردار مبتلا به عفونت ویروسی کووید 19 مورد مطالعه قرار گرفتند. در این مطالعه ، تب در بارداری، سرفه، تب بعد از زایمان،گلودرد،تنفس سخت، درد عضلانی،خستگی،ضعف، اسهال،سردرد، کاهش اشتهاء به عنوان علائم بالینی در زنان مبتلا به عفونت ویروسی کووید 19 مورد بررسی قرار گرفت. نتایج نشان داد که سرفه و تب بعد از زایمان به عنوان شایعترین علامت در مبتلایان بوده است. همه مبتلایان، استفاده از اکسیژن تراپی،داروهای ضد ویروس، آنتی بوتیک به عنوان راه های درمان در مبتلایان بکار برده شدند. در بررسی نتایج بارداری، موردی از مرده زایی گزارش نشد. اما حدود نیمی از موارد( 4 مورد از 9 مورد) زایمان پره ترم داشتند (1).
در مطالعه دیگر تعداد 15 نفر از زنان باردار مبتلا به عفونت ویروسی کووید 19 در سن حاملگی 12 تا 38 هفته بارداری مورد مطالعه قرار گرفتند.در این مطالعه سرفه و خستگی و درد عضلانی به عنوان شایعترین علامت در مبتلایان بوده است. مداخلات درمانی با استفاده از اکسیژن تراپی،داروهای ضد ویروس، آنتی بیوتیک انجام شدند. در 11 مورد از شرکت کنندگان در مطالعه تا پایان بررسی زایمان نموده بودند و بارداری در 4 نفر دیگر ادامه داشت. در اغلب شرکت کنندگان سزارین نوع غالب زایمان بود( 10 مورد از 11 زایمان)(9). در مطالعه دیگر41 نفر از زنان باردار مبتلا به عفونت ویروسی کووید 19 در سن حاملگی 22 تا 40 هفته بارداری مورد مطالعه قرار گرفتند.بر اساس نتایج تب قبل و بعد از زایمان، سرفه، تنفس سخت و بی اشتهایی به عنوان شایعترین علامت در مبتلایان بوده است. موارد مرگ مادر و نوزاد در این مطالعه صفر گزارش شده است(10).
نتایج مطالعات در زمینه انتقال عمودی COVID-19 از مادر به جنین مطرح کننده ابهاماتی است که نیاز به مطالعه بیشتر را می طلبد.در مطالعه ای افزایش خفیف آنزیم قلبی درنوزاد مبتلا شده از مادر دارای عفونت گزارش شد (2). در مطالعه دیگر علائم تب، افزایش تعداد تنفس، استفراغ و پنومونی از علائم واضح در نوزادان متولد شده از مادران مبتلاء به COVID-19 بود(3). با توجه به بار سنگین مرگ و میر و ناتوانی های متعاقب ویروس کرونا در دنیا، و پیش بینی پیک جدید و طوفانی ابتلا در آبان ماه سال آینده، در پژوهش حاضر محققین در نظر دارند شیوع و پیامدهای بارداری در زنان مبتلا به COVID-19 را بررسی نمایند. امید است که با اجرای این طرح، ضمن شناسایی و کمک به مادران و نوزادان با عوارض خاص یا طولانی مدت، عوامل خطر مرتبط با این عوارض را بررسی گردد. به این امید گامی پیش رونده در تجزیه و تحلیل دقیق داده های مرتبط با وضعیت مبتلایان و بهبود کیفیت درمان و کاهش مرگ و میرها در این گروه های حساس برداشته شود.
Technology and Research Information System
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2021
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Detection of Surface Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Hospital wards
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0
FA
Azra
Kenarkoohi
Ilam University of Medical sciences, Ilam, Iran
shahab
falahi
Ilam University of Medical Sciences, Ilam, Iran
Mohammad
Karimian
Department of Surgery, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Firooz
Balavandi
Department of Cardiology, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Elham
Bastani
Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Abbas
Ghaysouri
Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Technology and Research Information System
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2021
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Evaluation the antibiotic resistance pattern and persister cells in Helicobacter pylori collected from patients referring to Mostafa Khomeini hospital, Ilam, Iran and determination the recurrent of infection.
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0
FA
parvin
bahmani nezhad
Sobhan
Ghafourian
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Behzad
Badakhsh
Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Ebrahim
Kouhsari
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
نمونه های بالینی هلیکوباکتر پیلوری از نمونه بیوپسی توسط پزشک متخصص از بیماران با علائم بیماری های گوارشی فوقانی از ناحیه آنتروم معده از بیماران مراجعه کننده به مطب پزشکان که به طور معمول تحت آندوسکوپی گوارشی – معدی قرار گرفته اند ،جمع آوری می شود سپس نمونه ها در محیط انتقالی BHI broth می باشند و به آزمایشگاه منتقل و هموژنیزه می شوند.سپس کشت بر روی محیط اسکیرو در شرایط میکروآئروفیلیک انجام می شود وانکوبه می کنیم در مرحله بعد جهت شناسایی هلیکو باکتر پیلوری از تست های تاییدی اوره آز. اکسیداز وکاتالازاستفاده می کنیم سپس تعیین مقاومت به کلاریترومایسین، تتراسیکلین، آموکسی سیلین و مترونیدازول با استفاده از روش دیسک دیفیوژن انجام می شودو در ادامه از نمونه های حساس ، بررسی پرسیستر با روش لیزوزیم و تایید با بررسی 5 برابر MIC انجام خواهد شد.بعد از آن استخراج DNA انجام می دهیم وجهت مشخص نمودن وجود هلیکو باکتر پیلوری تکثیر ژن های ureA با استفاده از واکنش زنجیره پلیمراز انجام می گیرد، درنهایت فالوآپ بیمارانی که پرسیستر دارند را به دوصورت درمان در invitro وinvivo تحت درمان با آنتی بیوتیک های تتراسایکلین وآمینوگلیکوزیدهای اضافه شده به درمان انجام خواهد گرفت.
Technology and Research Information System
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2021
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investing the Relationship between spirituality with Aggression and individual persistence in students of Applied Academic clinics of ilam city in the year of Education of 1396- 1397
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FA
Yasamanzahra
Sadeghifard
Ilam
Fathola
Mohamadian
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
Yousef
Veisani
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
Technology and Research Information System
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2021
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Prevalence of isoniazid or rifampin resistance (mono-drug resistance) Mycobacterium tuberculosis strains isolated from patients in the Ilam and Kermanshah provinces
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FA
Hossein
Kazemian
Department of Microbiology, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
درمان رایج برای عفونت توبرکلوزیس استفاده از رژیم چند دارویی بوی‍ژه ریفامپین و ایزونیازید است که بیشترین تاثیر را بر روی مایکوباکتریوم توبرکلوزیس دارند. اگر چه استفاده از این داروها در درمان این عفونت بسیار موثر است، ظهور سویه های مایکوباکتریوم توبرکلوزیس مقاوم به ایزونیازید و ریفامپین (MDR)، کارایی این رژیم درمانی استاندارد را کاهش داده است .(2-5)از طرفی گسترش سویه های مقاوم به هر یک از این داروها بطور جداگانه(mono-drug resistance) نحوه ی درمان را پیچیده تر می سازد. درمان سویه های مقاوم به ایزونیازید با رژیم دارویی استاندارد موفقیت آمیز نبوده و احتمال ایجاد سویه های MDR را بالا می برد، و سویه های مقاوم به ریفامپین نیز به دوره درمان طولانی تری نیاز دارند (6, 18, 19). علاوه بر آن با شناسایی موتاسیون های غالب و مقایسه آنها می توان هدف مناسبی برای تشخیص سریع سویه های مقاوم ارائه کرد. لذا شناخت الگوی حساسیت و موتاسیون های غالب سویه های مایکوباکتریوم توبرکلوزیس مقاوم به دارو برای تشخیص بهتر و سریع، جلوگیری از درمان ناکارامد و بهینه سازی اثرات رژیم های چند داروی ضروری به نظر می رسد و این امر ما را قادر می سازد تا احتمال درمان و تشحیص سریع را افزایش دهیم و از گسترش سویه های مقاوم به دارو جلوگیری کنیم.
Technology and Research Information System
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2021
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Comparison between the efficacy of saccharomyces boulardii and placebo on treatment of pediatric functional abdominal pain in Ilam during 2017-2018
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0
FA
Gholamreza
Kalvandi
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
ali
dehdashtizadeh
Medical School
Naser
Abbasi
Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran
Kourosh
Sayehmiri
Psychosocial Injuries Research Center, Ilam University of Medical sciences, Ilam, Iran
Introduction:
Functional abdominal pain is a continuous or nearly continuous pain.There is no
relationship between physiological events and pain.The pain will lose some os daily
functions and is not feigned.There isn't sufficient symptoms to meet criteria for
another functional gastrointestinal disorder.This criteria must be fulfilled for the last 3
months with symptom onset at least 6 months prior to diagnosis.The pain is very
common in children and although benign in nature is associated with anxiety, school
absenteeism, frequent clinic visits, unnecessary testing and significant economic
burden.
Material and methods:
This study was conducted in the form of double blind clinical trial on a statistical
population of 104 children aged 5-15 years old who were suffering from functional
abdominal pain with the above criteria. In this study, after blood, urine and stool
sample analysis and performing an abdominopelvic sonography to rule out organic
disorders, the patients were divided into two groups: One group went under treatment
with saccharomyces boulardii (250mg BDS) and the other group started the process
using placebo. The patients took drug or placebo for three weeks and were also
followed for three weeks without medication. During this six week period, the severity
of the patient’s pain was assessed by trained mothers based on oucher pain scale.
Eventually the data was analyzed by statistical software SPSS.
Results:
57 of the patients were girls and the other 47 were boys. 55% of the patients were 5-10
years old and 45% were 10-15 years old. Using variance analysis, we compared the
pain score in treatment and control groups and found out that the drug effects show no
significant difference in various age (p-value: 0.928) or sex (p-value: 0.437) groups.
Comparing the control and treatment groups, Treatment with saccharomyces boulardii
was proved to be effective (p-value: 0.00); and the least amount of pain and the
highest difference between the two groups was seen in the fifth week.
Conclusion:
Considering the effectiveness of saccharomyces boulardii in treating children’s
functional abdominal pain, this probiotic can be used to cure this pain, which will
result in reduced school absenteeism, anxiety, frequent clinical visits and economic
burden.
Technology and Research Information System
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2021
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Thyroid dysfunction in Iranian pregnant women: A systematic review and meta-analysis
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FA
Milad
Azami
Ilam University of Medical Sciences, Ilam, Iran
Mehdi
Shokri
Department of Pediatrics, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Tayebeh
Rashidian
Department of Obstetrics and Gynecology, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Gholamreza
Badfar
Ahvaz Jundishapour University of Medical Sciences
Fatemeh
Kazemi
Qazvin University of Medical Sciences
Background
Thyroid dysfunction during pregnancy is associated with adverse outcomes for both mother and fetus. The present meta-analysis was conducted to evaluate thyroid dysfunction in Iranian pregnant women.
Methods
We registered this review at PROSPERO (registration number: CRD42020166655). The research steps in this systematic review and meta-analysis were performed according to the MOOSE protocol, and finally, reports were provided based on the PRISMA guidelines. The literature search was performed in October 2019 using the international online databases, including Web of Science, Ovid, Science Direct, Scopus, EMBASE, PubMed/Medline, Cochrane Library, EBSCO, CINAHL, Google Scholar as well as national databases were reviewed. Data were extracted after applying the inclusion and exclusion criteria and qualitative evaluation of the studies. I2 index and Q test were used to assess differences in studies. All analyses were performed using Comprehensive Meta-Analysis Software. P-value less than 0.05 was considered statistically significant. We identified 1261 potential articles from the databases, and 426 articles remained after removing the duplicate and unrelated studies. After evaluating the full text, 52 articles were removed.
Technology and Research Information System
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2021
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Frequency of genes encoding proteins involved in iron absorption in clinical and saprophytic isolates of Klebsiella pneumonia from Ilam hospitals Ilam
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FA
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
tahereh
elhaki
Department of medical microbiology
Despite the epidemiological significance of Klebsiella pneumoniae, few studies have been performed on the importance of siderophores in the pathogenicity of this species. The frequency of genes encoding proteins involved in iron uptake and their prevalence among saprophytic and clinical strains of Klebsiella pneumoniae in Ilam hospitals should be investigated. In the field of treatment methods, this pathogen was focused on this category.
Technology and Research Information System
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2021
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Genetic Analysis of Multiple Drug-resistant Klebsiella pneumoniae Isolatesby Pulsed-field Gel Electrophoresis
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0
FA
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
maria
teimourpour
Department of Microbiology
Hospitals such as pneumonia, urinary tract infections, septicemia, bacterial meningitis and biliary tract infections. Klebsiella is a major cause of nosocomial infections, especially among neonatal and intensive care unit patients with high mortality rates over the past two decades. The incidence of infections caused by multidrug-resistant Klebsiella species has increased. Multidrug resistance in Klebsiella specimens is associated with health care, using only carbapenems as the last possible line of antibiotic defense for infection. Unfortunately, since the early 2000s, Klebsiella strains of multidrug-resistant specimens (MDRs) have begun to produce carbapenemases encoded by plasmids. Which quickly spread to outpatients and hospitalized patients. There are methods for detecting the occurrence of an epidemic from related and unrelated strains as well as comparing specimens at the subspecies level, the most important of which is the epidemiological typing method that brings us closer to this goal. These methods rely on enzymatic cleavage and typing based on PCR and PFGE, which explore the molecular epidemiology of Klebsiella's sample and facilitate cognitive facilitation, as well as isolated strains to better understand the epidemiology of MDR strains. PFGE is often considered the gold standard of other methods, which is a reference method for typing and identifying many organisms, including Klebsiella. The aim of this study was to evaluate the pattern of antibiotic susceptibility as well as PFGE in order to study the molecular epidemiology of Klebsiella strains isolated from hospital clinical patients. Given the importance of MDR in bacteria, the need for new programs to prevent their spread is evident. The misguided policy of overuse of antibiotics, resource constraints, and lack of facilities in hospitals has contributed to these conditions, which have limited the effectiveness of many antimicrobial agents, resulting in significantly reduced treatment choices, which is why Doctors go straight to strong antibiotics, and prescribe the strongest antibiotics. The need for further studies in this field, as well as reducing the use of antibiotics and prescribing antibiotics by physicians is essential due to the results of antibiotic susceptibility testing. In this study, we tried to study the genetic analysis of Klebsiella isolates with multiple drug resistance and antibiotic resistance pattern and determine their types, because to prevent and control infections and to select appropriate treatment, genetic analysis and epidemiological study of these isolates are required. . In this study, by recognizing the clonal relationship of Klebsiella sample isolates and examining their genetic diversity, it can be useful and practical in identifying the source and controlling infections caused by Klebsiella sample.
Technology and Research Information System
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2021
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Genetic Analysis of Multiple Drug-resistant Escherichia coli Isolates by Pulsed-field Gel Electrophoresis
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FA
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
masoumeh
Hatamilak
Department of Medical Microbiology
Enterobacteriaceae, especially Escherichia coli, are the most common cause of nosocomial and community-acquired infections. The emergence and spread of Escherichia coli strains with multiple drug resistance complicates treatment for multiple severe infections.
In this study, pulse field gel electrophoresis (PFGE) method is used for genetic analysis of Escherichia coli strains with multiple drug resistance. Pulse field gel electrophoresis (PFGE) is one of the most useful developments in molecular epidemiology for the past few decades and is now considered the gold standard for molecular typing of microorganisms.
In this study, we have tried to study the genetic analysis of Escherichia coli isolates with multiple drug resistance and the pattern of antibiotic resistance and determine its types, because to prevent and control infections and to select appropriate treatment, genetic analysis and epidemiological study of the region Isolates with drug resistance are required.
Technology and Research Information System
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2021
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the study of frequency of neisseria meningitides and moraxella catarrhalis in the oropharynx of children under 6 years in ilam in 2015-2014
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0
FA
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Ziba
Mirnaseri
Department of medical microbiology
A close correlation existed between asymptomatic oropharyngeal colonization of bacterial pathogens and a range of pediatric respiratory disease, also, if this pathogens contain the iron and virulence genes, person to person transmission and subsequent disease of this asymptomatic colonization, Known as a potential risk in children. Thus, in this study we evaluated the frequency of asymptomatic carriers of Neisseria meningitides and Moraxella catarrhalis in healthy childrenIn this study we assess the frequency of Neisseria meningitides and Moraxella catarrhalis in oropharynx of 123 children from 2 to 6 years old in kindergartens of Ilam province, iran, by specific methods including culture and phenotypic diagnosis as well as PCR and Real-time PCR; also iron and virulence genes was evaluated in this bacteria using the PCR method. Finally, statistical analysis was performed to evaluate the colonization of both bacteria in children and the relationship between variables that affecting the frequency of these bacteria.The majority of obtainedbacteria isolated in this study were positive for the presence of virulence and iron genes, given that the presence of these genes for survival of these bacteria in the body is essential; children, who are carriers of these bacteria, were more at risk to develop respiratory diseases by pathogenic bacteria. Finally, due to the study of the relationship between variables and the prevalence of these bacteria appears that most children, who have asymptomatic carriage with Neisseria meningitidis, were present in large families with low economic status, which reflects the importance of the environment and socio-economic level of families in the development of these potentially pathogenic bacteria in the oropharynx of children. So, when these children are placed in high-density locations such as daycare centers, than other children, are more susceptible to asymptomatic colonization of respiratory pathogens and then in the long term may be at risk for respiratory disease.
Technology and Research Information System
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2021
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Title: The study of frequency of oropharynx microbiome among healthy children under 6 years old in Ilam city during 2015
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0
FA
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
maryam
zamirnasta
Department of Microbiology
Acute respiratory infection is one of the primary diseases that causes high morbidity and mortality in children, especially in developing countries, where 70% of deaths are in Africa and Southeast Asia (1). . The latest statistics show that approximately 150 million new cases of pneumonia are diagnosed worldwide each year, more than 90% of which occur in developing countries and 30% of annual deaths in children under 5 years of age. Is (2). In Iran, several studies have been performed on selected populations of children with acute respiratory infections in different parts of the country, which have yielded different results, so an accurate statistical picture of the extent and importance of acute respiratory infections is not available (3). . Acute respiratory infection is often caused by a new invasion or abnormal release (development) of a specific pathogen into the airway, which in addition to the host defense also affects the incidence and severity of infection (4). , Microbiome refers to the overall microbial community and its biomolecules in a defined environment (5). It describes the fundamental role of microbiome in human health (6).
Research based on culture studies and, more recently, culture-independent methods have identified a microbial community in the lower respiratory tract of a healthy individual. (7).
Therefore, studying and informing about the prevalence of bacteria and viruses in pediatric uropharynx and also better understanding of bacterial colonization and their interaction, can be effective in predicting changes in bacterial ecology and design control strategies (including interference in colonization) . In particular, determining the rate of asymptomatic colonization with potential pathogens is important to predict the spread of the disease in the community and to design strategies for prevention and treatment. Therefore, respiratory infections in both developing and developed countries have a heavy economic burden on the family and society. Finally, considering the importance of respiratory infections in our country, in this study we try to investigate the prevalence and frequency of oropharyngeal microbiome in children under 6 years of age in Ilam by culture method and its relationship with the underlying variables to be evaluated. , And thus provide the necessary ground for further studies by researchers in the future
Technology and Research Information System
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2021
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Nasal and Oropharyngeal carriage of Streptococcus pneumonia and Haemophilus influenza among children under 6 years old in Ilam city 2014-2015
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0
FA
fatemeh
mansournia
Medical School
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Background and Aim: A close correlation are exist between asymptomatic oropharyngeal colonization of bacterial pathogens and a range of pediatric respiratory disease and if this pathogens contains the iron and virulence genes, person to person transmission and subsequent disease of this asymptomatic colonization, are a potential risk for children. Thus, in this study we evaluate the frequency of asymptomatic carriers of Streptococcus pneumoniae and Haemophilus influenzae in healthy children.
Material and Methods: In this study we assess the frequency of Streptococcus pneumoniae and Haemophilus influenzae in oropharynx and nazal cavity of 123 children from 2 to 6 of age in the kindergartens of ilam province by specific methods of culture and phenotypic diagnosis as well as PCR and Real-time PCR.
Results: The prevalence of asymptomatic colonization of Streptococcus pneumoniae and Haemophilus were 30/1 percent and 17/1 percent, respectively. Likewise a considerable relation was found between colonization of Streptococcus pneumoniae and Haemophilus influenzae in children that are resides in houseful and poor families.
Discussion and Conclusion: Asymptomatic colonization of pathogens such as Streptococcus pneumoniae and Haemophilus influenzae in the oropharynx in childhood, disrupt the unique homeostasis in Microbiota of this region and because of that respiratory microbiota, shaping the respiratory tract microbiota composition and consequent diseases in the future, thus appointment of asymptomatic colonization of these bacteria in oropharynx of healthy children can be helpful for find ways to interfere with colonization of this pathogens or prevention of therefrom disease. Finally, this study can be used as a basis for further studies in the field of asymptomatic colonization of pathogenic bacteria in the oropharynx of healthy children to be used in the future.
Key Words: Asymptomatic colonization, children, oropharynx and nasal cavity, Streptococcus pneumoniae, Haemophilus influenzae, Real-time PCR.
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Technology and Research Information System
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2021
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مطالعه ی فراوانی شیگاتوکسین-1 در جدایه های شیگلا فلکسنری جداشده از بیماران مبتلا به اسهال در شهراهواز به روش Real-Time PCR
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0
FA
nahid
mahdian
Medical School
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Sobhan
Ghafourian
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Diarrheal is the second most prevalent causes in under five-year old children worldwide. Shigella spp. which renders dysentery in children are mostly prevailed in underdeveloped countries, where hygiene were poor practices. Shiga toxin is responsible for fatal manifestations of shigellosis including dysentery, hemorrhagic colitis, uremic-hemolytic syndrome, etc. By increasing our knowledge on toxin presence in isolates, effective treatment can be done in future and prevented from further complications. we investigated the frequency of stx1 gene in Shigella spp. (except S. dysenteriae) isolated from diarrheal patients in Ahvaz city, southwestern Iran.
Methods: During a two-year period, 227 Shigella species including 60 S. flexneri, 157 S. sonnei and 10 S. boydii were obtained from diarrheal patients. Upon DNA extraction, PCR was applied for stx1 gene detection in validated isolates.
Findings: Based on our findings, none of the organisms were recognized to be positive regarding the stx1 gene.
Conclusion: The lack of toxin production among the Shigella spp in this area shows that the encoding shiga-toxin phage is not carried by these isolates. However, regarding the emergence of this phage in other territories of the world and the unknown condition for transmission to other species, we can’t make an absolute decision on its absence in this region.
Technology and Research Information System
4
3
2021
12
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Effect of Toxin – Antitoxin System on Expression of Virulence Factors in Shigella flexneri isolated from diarrheal patients in Ahvaz city
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0
FA
Nourkhoda
Sadeghifard
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Iraj
Pakzad
Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
mehrnoush
safikhani
department of medical microbiology
Among widespread cause in gastrointestinal disorders we can mention shigella flexneri . Because of its complicated virulence factors, it seems to be good to investigate S. flexneri genome and recognize regulatory sequences. Toxin antitoxin systems is one of regulatory sequence that have important role in cellular process so we choose mazEF and relBE for more analysis and its effect on virulence factors VirF, IpaB and shigella enterotoxin1.
Technology and Research Information System
4
3
2021
12
1
Epidemiology of gastroesophageal reflux disease in Iran; a systematic review and meta-analysis
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0
FA
Milad
Azami
Ilam University of Medical Sciences, Ilam, Iran
Mohamadreza
Hafezi Ahmadi
Biotechnology and Medicinal Plants Research Center, Ilam University of Medical sciences, Ilam, Iran
Mohammad
Karimian
Department of Surgery, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Majid
Salamati
Department of Surgery, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Hassan
Nourmohammadi
Department of Internal Medicine, School of Medicine, Ilam University of Medical sciences, Ilam, Iran
Background
Gastroesophageal reflux disease (GERD), which leads to acid reflux into the esophagus, is a common gastrointestinal disorder. Several studies have shown the prevalence of GERD in Iranian population, but their evidence is contradictory. Therefore, the present study was conducted to investigate the epidemiology of GERD in Iran.
Methods
The entire steps of this systematic review and meta-analysis were based on the MOOSE protocol, and the results were reported accordance with the PRISMA guideline. This review is registered on PROSPERO (registration number: CRD42020142861). To find potentially relevant published articles, comprehensive search was done on international online databases Scopus, Science Direct, EMBASE, PubMed/Medline, CINAHL, EBSCO, Cochrane Library, Web of Science, Iranian online databases and the Google Scholar search engine in June 2019. Cochran test and I2 index were used to assess the heterogeneity of the studies. Data were analyzed using Comprehensive Meta-Analysis software ver. 2. The significance level of the test was considered to be P < 0.05.
Technology and Research Information System
4
3
2021
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An investigation in knowledge, attitude and performance of students of Ilam University of Medical Sciences about the use of industrial drugs (Misuse of Stimulant Medication) in 2019
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0
FA
Masoumeh
Shohani
Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical sciences, Ilam, Iran
abas
nasrolahi
lali
abedi
maryam
cheghini