@article{ author = {zabihirad, javad and zangana, Hamazeh and karimi, amin and havasi, lil}, title = {Affecting integrated health care on quality of life in older population in Malegshahi Township; 2015}, abstract ={سالمندی مهم ترین پدیده مردم شناختی اواخر قرن بیستم و شروع قرن بیست و یکم می باشد.  بر اساس تعریفی که افراد بالای 65 سال را سالمند محسوب می‌کند، سالمندی در حال حاضر دارای رشد 4/2 درصد در مقایسه با 7/1 درصد برای کل جمعیت می‌باشد و انتظار می‌رود که این رشد به 1/3 درصد در سال‌های آتی افزایش پیدا کند. جمعیت سالمندان از 600 میلیون در سال 2000 به یک میلیارد و دویست میلیون یعنی دو برابر در سال 2025 خواهد رسید (1). سلامتی حق اساسی هر انسان و یک هدف اجتماعی است و تمام دولت‌ها و حکومت‌ها موظف به تأمین سلامت افراد می‌باشند (2). تغییر در الگوی بیماری‌ها که کاهش میزان بیماری‌های عفونی و افزایش طول عمر و بیماری‌های مزمن را به همراه داشته، منجر به افزایش توجه به مفاهیم سلامتی و کیفیت زندگی طی دهه‌های گذشته گردیده است (3). چالش عمده واصلی بهداشت قرن بیستم افزایش امید به زندگی بود ولی چالش عمده قرن بیست و کیم، زندگی با کیفیت بهتراست. گرچه پیر شدن جمعیت از نتایج مثبت توسعه به شمار می‌آید ولی اگر برای مواجهه با آن درجهانی توسعه یافته آماده نباشیم اقتصادی و عدم کفایت خدمات اجتماعی، مراقبت‌های پزشکی و... سبب گردیده تا این قشر از آسیب‌پذیرترین اقشار جامعه باشند . ازاین‌رو توجه به کیفیت زندگی سالمندان و برنامه‌ریزی جهت ارتقاء کیفیت زندگی آنان ضروری است (4). بیماری‌های مختلفی چون سکته مغزی، دمانس و ضربه‌مغزی می‌تواند منجر به اختلالات شناختی شود.  وجود اختلالات شناختی جدی نه‌تنها باعث کاهش عملکرد شناختی فردی می‌گردد بلکه رفته‌رفته باعث احساس افسردگی و انزوای اجتماعی می‌گردد و فشار روانی فراوانی بر سالمندان و خانواده او وارد می‌کند (5). بسیاری از سالمندان به بیماری‌هایی مبتلا می‌شوند که ممکن است استقلال و کیفیت زندگی آنان را تهدید نماید. به‌طورکلی اگر سالمندان بیاموزند که چگونه باید باقیمانده عمر خود را در آرامش و آسایش بگذرانند، می‌توانند عوامل کاهش‌دهنده‌ی کیفیت زندگی خود را به نحو مطلوب تری متعادل سازند (6). اهمیت کیفیت زندگی و وضعیت سلامت تا حدی است که صاحب‌نظران معتقدند که بیشتر مراقبت‌های بهداشتی قرن حاضر بایستی بر بهبود کیفیت زندگی و وضعیت سلامت متمرکز گردد (7) کیفیت زندگی یک رویکرد معتبر برای گسترش تعریف سلامتی فراهم کرده به طوری که حوزه‌های سلامت جسمی، روانی و رفاه اجتماعی را نیز دربرمی گیرد (8) بنا به تعریف سازمان جهانی بهداشت، کیفیت زندگی درک افراد از موقعیت خود در زندگی ازنظر فرهنگ، سیستم ارزشی که در آن زندگی می‌کنند، بنابراین با نظر داشتن نیازهای خاص دوران سالمندی توجه به کیفیت زندگی سالمندان امری بسیار ضروری است (9). طرح ادغام یافته سلامت سالمندان یکی از طرح‌های بهداشتی است که از سوی وزارت بهداشت در حال اجرا است لذا بررسی تأثیر این طرح بر کیفیت زندگی سالمندان شهرستان ملکشاهی ضروری به نظر می‌رسد}, Keywords = {Quality of Life}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1871-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1871-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {byatipur, Zahra and Pakzad, Iraj and Sadeghifard, Nourkhoda and Khorshidi, Ali}, title = {The effect of chlorhexidine (CHX) and hydrogen peroxide (H2O2) on expression of biofilm formation related genes in Enterococcus faecalis}, abstract ={Biofilm formation causes many serious problems in the treatment in infections disease. In addition, bacterial biofilms in hospitals cause contamination and great damage to the health system. Hence, the purpose of the available study was to investigate antibacterial effect of chlorhexidine (CHX) and hydrogen peroxide (H2O2) on gene expression in Enterococcus faecalis biofilm.}, Keywords = {Biofilm, Chlorhexidine gluconate, Hydrogen peroxide, E.faecalis, Asa1, efaA, epaI, esp, qReal Time PCR}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1169-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1169-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {zabihirad, javad and Asadolahi, Khairollah and Veisani, Yousef and Momeni, Khalil}, title = {Investigating the direct and indirect costs of diabetes in Ilam city in 2018}, abstract ={}, Keywords = {direct and indirect costs, diabetes , Ilam}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-670-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-670-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Deldar, maryam and Sayehmiri, Kourosh and anbiaee, robab and Jalilian, Anahit}, title = {Predicting Ovarian Cancer Survival Times: Comparison Of Parametric Methods With Random Survival Forests}, abstract ={Background and Aim: Predicting survival time has many effective consequences in managing the quality of life for the rest of the patientchr('39')s life. On the other hand, survival data are highly variable and make accurate predictions difficult. Random survival forests by repeating tree construction and averaging the results of these trees cause reducing the prediction error and further generalizability of these results. This thesis compares the prediction error of the random survival forest model with the Cox and Weibull models in predicting the time to the first recurrence in patients with epithelial ovarian cancer. Materials and Methods: In this study, the data of 141 patients with ovarian cancer who referred to Imam Hossein Hospital in Tehran from 2008 to the end of 2018 were used. Cox regression, Weibull model, classification and regression tree, and random survival forest were fitted to the data to investigate the factors affecting the first recurrence of patients, respectively. Finally, using the C-Index and Brier score, the prediction error of these models were compared. Results: According to the results of random survival forest, metastatic tumor using the criterion (VIMP), with relative importance of 2.665 and minimal depth (MD) 2.349, tumor stage with relative importance of 1.993 and depth of 2.678, and maximum platelet count with relative importance of 2.132 and depth of 2.683 were effective variables. According to the Brier score, the random survival forest prediction error was 0.16 and the Cox model was 0.24. The C-Index error in the random survival forest was 0.34 and the Cox model was 0.42. Brier scores for the Cox and Weibull models were calculated to be approximately the same, so the random survival forest prediction error of the less than both Cox and Weibull models. Conclusion: Unlike classical methods, the random survival forest without the need for special presuppositions with less predictive error can well explain the variables of the response variable when exposed to high-dimensional data.}, Keywords = {ovarian cancer, random survival forest, parametric methods, relapse}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-540-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-540-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Mirzaei, Asad and khorshidvand, zohreh}, title = {A resurvey on the prevalence Blastocystis hominis of immunocompromised patients in wold: Systematic review and meta-analysis.}, abstract ={    اﻧﮕﻠﻬﺎ یﮑﯽ از ﻣﻬﻤﺘﺮیﻦ ﻋﻮاﻣﻞ ایﺠﺎدﮐﻨﻨﺪه ﺑﯿﻤﺎریﻬﺎی ﻋﻔﻮﻧﯽ در اﻓﺮاد دچار نقص سیستم ایﻤﻨﯽ هستند. اﻓﺮاد ﺗﺤﺖ درﻣﺎن ﺑﺎ داروﻫﺎی ﺷﻴﻤﻲدرﻣﺎﻧﻲ، مبتلایان به انواع بدخیمی، گیرندگان پیوند و مبتلایان به ایدز ﻧﺴﺒﺖ ﺑﻪ اﻓﺮاد ﻋـﺎدی، درﺻـﺪ ﺑﺎﻻﺗﺮی از آﻟﻮدﮔﻲﻫﺎی اﻧﮕﻠﻲ را ﻧﺸﺎن ﻣﻲدﻫﻨﺪ. بلاستوسیستیس هومینیس تک یاخته انگلی شایع در انسان است که انتشار جهانی داشته و به دفعات از نمونه های مدفوع در آزمایشگاه های انگل شناسی جدا میشود. ﻧﻘﺺ اﻳﻤﻨﻲ زﻣﻴﻨﻪ را ﺑﺮای اﺑـﺘﻼ ﺑـﻪ اﻧـﻮاع ﻋﻔﻮﻧـﺖﻫـﺎ ﻣـﺴﺎﻋﺪ ﻣﻲﻛﻨﺪ. ﻋﻔﻮﻧﺖ ﻫﺎی اﻧﮕﻠـﻲ ﺑـﻪ وﻳـﮋه اﻧﮕـﻞﻫـﺎی ﻓﺮﺻـﺖ ﻃﻠـﺐ، از ﻣﺸﻜﻼت اﺻﻠﻲ ﺑﻴﻤﺎران دﭼﺎر ﻧﻘﺺ سیستم اﻳﻤﻨﻲ اﺳﺖ.     علیرغم مطالعات متعددی که در نقاط مختلف جهان صورت گرفته است، اطلاعات جامع در خصوص اپیدمیولوژی آلودگی افراد دچار نقص سیستم ایمنی به بلاستوسیستیس هومسنیس در دسترس نیست. لذا این مطالعه مروری ساختاریافته به منظور جمع­آوری گزارشات حاصل از مطالعات انجام شده در نقاط مختلف دنیا و گردآوری اطلاعات به صورت یک مطالعه نظام­مند انجام می‌گیرد و امید است نتایج این مطالعه در راستای اقدامات پیشگیری و کنترل بیماری ایجاد شده با این انگل مفید واقع گردد.  }, Keywords = {B. hominis, AIDS, Metanalyses}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-465-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-465-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Valadbeigi, Hasan and Kouhsari, Ebrahim and Khadiv, Arezoo and Sayadi, Hojat and Sadeghifard, Nourkho}, title = {The prevalence of heteroresistance to clarithromycin and metronidazole in Helicobacter pylori : systematic review and meta-analysis}, abstract ={}, Keywords = {Helicobacter pylori ,heteroresistance,clarithromycin heteroresistance,metronidazole heteroresistance}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1108-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1108-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Basati, Gholam and Shams, Morteza and Majidiani, Hamidreza and Asghari, Ali and Nourmohammadi, Hass}, title = {Bioinformatics design of a fine-tuned multi-epitope protein for detection of human Toxocara canis infection in human}, abstract ={Serological investigation is the main method to achieve satisfactory results in Toxocara canis diagnosis. The accuracy of the native antigen used in the current diagnostic kits has proven to be insufficient as well as difficult to standardize. Therefore, significant efforts have been made to find alternative reagents as capture antigens. Multi-epitope peptides are potential diagnostic markers to improve the accuracy of diagnostic kits. The main aim of this study is the prediction and design of a novel synthetic protein consisting of multiple immunodominant B cell epitopes. Primary, secondary and tertiary structures of the proteins are analyzed by using several various online software (ExPasy, IEDB, ABCpred, SVMTriP). Then, B cell construct was assessed by machine learning and Physico-chemical approaches and finally, homology modeling of 3D structure of protein is evaluated.}, Keywords = {human Toxocara canis infection, fine-tuned multi-epitope protein, immunoinformatics}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1245-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1245-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Shams, Morteza and Basati, Gholam and Majidiani, Hamidreza and Nourmohammadi, Hassan and Azizi, Esfandyar}, title = {Leishmanolysin gp63: bioinformatics evidences of immunogenic epitopes in Leishmania major as possible vaccine target against cutaneous leishmaniasis}, abstract ={V}, Keywords = {leishmania major, Proteine, Vaccine}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1377-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1377-en.doc}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Pakzad, Reza and soltani, saber and zandi, milad and akhavanrezayat, sara and Hosseini, zeinab and Malekifar, Pooneh and Pakzad, Iraj and kakaei, Habib}, title = {The Ocular manifestations in COVID-19 patients: a systematic review and meta-analysis}, abstract ={The ocular tropism of respiratory viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is reported, and studies showed ocular manifestations in coronavirus disease 2019 (COVID-19) patient. The aims of the current systematic review and meta-analysis study will be to determine the prevalence of ophthalmic manifestation in COVID-19 patients. We will be searched the literature in Medline, Scopus, Web of Science, and Embase from December 1, 2019, until December 5, 2020, by using the main following MeSH keywords "SARS-CoV-2" and "ocular manifestations." The prevalence and 95% confidence interval (CI) will be calculated using binomial distribution and random effects. The meta-regression method will be utilized to investigate the factors affecting the heterogeneity.}, Keywords = {Ocular manifestation, COVID-19, systematic review, meta-analysis}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1287-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1287-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Aidi, Ali and Karimi, Elaheh and Bahmani, Mahmoud and hasankaviar, vahab}, title = {Analysis of Loranthus plant (Loranthus micranthus Linn.) (Herbivorous) by GC-SPME and HPLC-DAD methods and impact on inhibiting the growth and proliferation of Astinobacter pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa}, abstract ={The increasing spread of drug and antibiotic resistance among bacteria has led to more attention being paid to finding pharmacological methods of resistance and also finding natural remedies suitable with fewer side effects. Laurentus plant is collected from Ilam city in Ilam province and after drying its leaves, essential oil and hydroalcoholic extract are prepared. The chemical composition of essential oil and leaf extract of Laurentus plant is measured by HS-SPME, GC-MS and HPLC-DAD methods. Medicinal plants are of particular interest due to their wide range of bioactive compounds as a potential source of new chemotherapy drugs, because herbal medicines are more compatible with living organisms, including the human body, due to their natural origin than chemical drugs. And cause fewer side effects. Therefore, by examining the antimicrobial effect of this plant, an effective step can be taken in its commercialization and use scientifically. And Pseudomonas aerosinosa.}, Keywords = {Chemical Analysis, Laurentus, GC-MASS}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1438-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1438-en.DOCX}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Zakariaee, Seyed Salman and Naderi, Negar and RazaeeMolood, Danial}, title = {Prognostic accuracy of visual lung damage computed tomography score for mortality prediction in patients with COVID-19 pneumonia, a systematic review and meta-analysis}, abstract ={Prognostic accuracy of visual lung damage computed tomography score for mortality prediction in patients with COVID-19 pneumonia, a systematic review and meta-analysis}, Keywords = {Prognostic accuracy, Covid-19, Computed tomography, Mortality, CT, Pneumonia}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1647-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1647-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Azami, Milad and Karimian, Mohammad and Salamati, Majid and Kazemi, Fatemeh and Adibi, Amir and Ranjbar, Rez}, title = {Prevalence of dyspepsia in Iran: A systematic review and meta-analysis}, abstract ={Background: Dyspepsia is one of the most common gastrointestinal disorders. The aim of this study was to evaluate the prevalence of dyspepsia in Iran. Patients and methods: This study was registered in PROSPERO with code (CRD42019148610) and conducted based on Meta-analyses Of Observational Studies in Epidemiology) MOOSE) and reporting was done in accordance with the reporting was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). Systematic literature search was done in July 2019 using international online databases PubMed/Medline, Web of Science (ISI), Cochrane Library, Scopus, EMBASE, Science Direct, EBSCO, CINAHL, and national online databases Magiran, SID, RICST, IranDoc, Iranian National Library and Barakat Knowledge Network System and as well as Google Scholar. Heterogeneity was assessed using I2 and Chi-square tests. All analyses were performed with Comprehensive Meta-Analysis Software}, Keywords = {Prevalence, dyspepsia, Iran, meta-analysis}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-673-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-673-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {saeidi, ali and Jalilian, Mohsen and mahaki, behz}, title = {Effectiveness of educational program based on Transtheoretical model on physical activity stage of change in high school students of sharableh city}, abstract ={Effectiveness of educational program based on Transtheoretical model on physical activity stage of change in high school students of sharableh city  }, Keywords = {transtheoretical model, physical activity, adolescent, health education}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1926-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1926-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Ghafourian, Sobhan and khorami, hamed and aziznezhad, maysam and mahdian, somayeh}, title = {Design and manufacture of PH meter device with automatic creation of liquid with adjustable PH}, abstract ={PH measurement is one of the most common decomposition techniques used to determine the acid or base strength of a sample. This quantity can be done electronically using acid and base color reagents (in the form of paper or solution with color scale) and electronically. PH is measured electronically using an electrode. An electrode is an electrochemical sensor that includes a detector electrode and a reference electrode. The history of measuring the acidity of liquids electrically dates back to 1906, when Max Cremer, in his study of liquid interfaces (the interaction between liquids and solids), realized that the interface between liquids could be blown by blowing a bubble. Small glass and put one liquid inside it and another outside to be studied. In this way, an electrical voltage was generated that could be measured. The H-gauge measures the electrical potential between the mercury chloride at the reference electrode and its potassium chloride liquid, the unknown liquid, the solution inside the glass electrode, and the potential between this solution and the silver chloride. But only the potential between the unknown liquid and the solution inside the glass electrode changes from one sample to another. Therefore, the remaining voltages are measured without being present in the equation. The white mercury reference electrode consists of a glass tube with a potassium chloride (KCl) electrode in close contact with the mercury chloride element at the end of the KCl element. It is a brittle compound, which is in contact with a liquid connection tip made of porous ceramic or similar material. These types of electrodes are not easily contaminated with heavy metals and sodium. The glass electrode consists of a rigid glass tube to which a thin glass bubble is attached. Inside it is a known solution of potassium chloride (KCl) as a 7 + PH buffer. Establishes the interior. To reduce electronic interference, the probe is protected by a foil sheath, often found inside a glass electrode. Due to the time consuming nature of measuring the pH of materials with the current pH meter, we decided to use a device that can provide the appropriate pH in a hygienic environment, taking into account the minimum time and the intervention of human resources. . Therefore, the new device is able to do this and on the other hand, it creates this advantage so that we can localize the construction of this device and reduce costs by preventing transfers and currency. Liquid injection to achieve the required pH accurately and uniformly with a mixer at a gentle and uniform speed is one of the innovations of this design, which greatly reduces the risks of working with the solution by manpower. There are many examples of PH meters, but there is no example that creates a liquid with a selected pH and records events in diagrams, and if there is, it is limited and out of reach.}, Keywords = {pH meter, acidic, basic}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1919-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1919-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Ghafourian, Sobhan and Mahmoudi, mi}, title = {Toxin Antitoxin Systems as a Reliable Antimicrobial Target for Inhibition of Biofilm Formation in Pseudomonas aeruginosa}, abstract ={The ability of Pseudomonas aeruginosa to produce biofilm made it as a hard crisis to treat with current antibiotics. Some genes in bacteria like toxin antitoxin (TA) loci are responsible for regulating of the other genes like genes involved in biofilm production. So, by disrupting of these TA loci, they can be focused as novel anti-biofilm targets. Therefore, the current study aimed to evaluate different TA loci to find the reliable target for prevention of biofilm production. For this purpose, 30 P. aeruginosa clinical isolates were subjected to biofilm production and presence of different TA loci. For target discovery the target should be presence in biofilm producer isolates and should be functional means more express in strong biofilm producer bacteria; finally by knocked out of these TA loci the biofilm producer P. aeruginosa should become no biofilm producers. So, among 30 isolates relBE TA loci were presented in biofilm producers P. aeruginosa and if be presented in no biofilm isolates, it showed no expression. The functionality was confirmed by RT-qPCR, which the results demonstrated that the relBE TA loci expression was more in stronger biofilm producer isolates. Also, our findings showed by knocked out of relBE TA loci the isolate that be biofilm producer changed to no biofilm producer. The current study defined the role of relBE TA loci to regulate the biofilm production and showed relBE TA loci as a reliable anti-biofilm target in P. aeruginosa.}, Keywords = {Pseudomonas aeruginosa, toxin antitoxin systems, target discovery}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1901-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1901-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Ghafourian, Sobhan and TaheriKalani, Morovat and Pakzad, Iraj and Sadeghifard, Nourkho}, title = {Uropathogenic Bacterial and Antibiotic Resistance Pattern among patients Refereeing to Imam Khomaini Hospital, Ilam, Iran}, abstract ={Background & objectives: Urinary tract infections (UTIs) caused by extended-spectrum beta lactamase (ESBL)-producing bacteria، Metallo-Beta-Lactamase (MBL)  have become a growing problem worldwide. The aim of this study was to Uropathogenic Bacterial and Antibiotic Resistance Pattern among patients Refereeing to Imam Khomaini Hospital, Ilam, Iran Methods:  In this cross - sectional study of patients with urinary tract infection in Imam Khomeini Hospital in Ilam were evaluated over a period of 9 months. All isolates were identified by routine biochemical methods and antimicrobial  susceptibility testing carried out by Kirby-Bauer method. Phenotypic confirmation test to detect ESBL, MBL, MRSA, VRSA and VRE antibiotic disk diffusion method was performed by disc. The results were interpreted according to the CLSI standard. Identification of genes SHV, CTX-M, TEM, VanA, mecA, bla VIM and bla IMP PCR was performed using the method. Results: 114 isolates were examined by 61.4% Escherichia-coli, 7% Citrobacter freundii, 7% Pseudomonas aeroginosa, 8% Enterobacterccloacae, 8% of Klebsiella poneumoniue, 4.1%Proteus mirabilis, 0.9% Acintobacter baumannii, 0.9% of Staphylococcus aureus, 0.9% Enterococcus faecalis and 1.8% diphtheroids were separated. Conclusion: Most isolates were resistant to the antibiotic cotrimoxazole (55%), cefotaxime (49%), ceftriaxone (41%) showed. 46 isolates (49.5%) ESBL were considered. Escherichia-coli 63%, 8% Citrobacter freundii , Pseudomonas aeroginosa  6%, 6%, Enterobacter cloacae, Proteus mirabilis 6%, 6% and 2% of Klebsiella pneumoniae were Acintobacter baumannii . In total, only 6.4% of the isolates were considered as phenotype MBL. The genotyping PCR method was shown that genes VIM1, VIM2 and IMP were not mentioned in any of the isolates. In between isolates of Gram-positive, none genotyped MRSA, VRSA and VRE was isolated. Only one (100%) Staphylococcus aureus isolates, for phenotypic VRSA was considered. The results of this study, as well as Gram-negative bacteria Enterobacteriaceae family, are the main factors that cause urinary tract infections.The results of this study show that the ESBLs produced in bacteria isolated from patients with urinary tract infection, which is up almost 49.5% of the isolates were ESBL and 6.4% MBL. Since, according to the study in Ilam high prevalence of ESBL-producing bacteria in the urinary tract infections and the prevalence is rising MBL. It is recommended that programs be seriously considered antibiotic use and prescribing of antibiotics is organized. As well as more studies are done on the MBL.  }, Keywords = {urinary tract infection(UTI), (ESBL) Extended-spectrum Beta-lactamasea (MRSA) Methicillin Resistance Staphylococcus Aureus disk diffusion method}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1866-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1866-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Ghafourian, Sobhan and jalili, mahsa and Pakzad, Iraj}, title = {Anti- persister effect of alcoholic extract of peganumharmala in Pseudomonas aeruginosa clinical isolates}, abstract ={Abstract Unfortunately, today multidrug resistant (MDR) bacteria are very common in communities and could be a serious threat to human health. Consequently, bacterial populations contain new mechanism of survival strategy in hostile environments or antibiotic exposure. One of the most important mechanisms is persister cell formation in bacteria. Persister cell can be one of the important causes of chronic infections. Also, there are many challenges for combating persister cell. The discovery of new drugs and appropriate therapies in this area is very necessary. So, the purpose of the present research was discovery of an anti-persister drug against Pseudomonas aeruginosa clinical isolates. For this purpose, thirty P. aeruginosa clinical isolates were used for more analysis. Antibiotic susceptibility test and persister cell assay were performed. Finally, Peganum harmala was investigate as a likely source of an anti-persister cell drug. The finding demonstrated that concentration of 35ug/ml completely has the anti-persister properties. So, it can be herbal candidate against persister cells but further analysis including in vivo study and finding the main component should be done to commercial this herb as new anti-persister drug.  }, Keywords = {Persister cell, Peganum harmala, Pseudomonas aeroginosa}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1862-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1862-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {taghinezhad, Fakhredin and Kafashian, Mohamadreza and Kalvandi, Gholamreza and Shafiei, Elham}, title = {Use of artificial neural networks to predict Epidemiological and Clinical risk factors for COVID-19 patient mortality in Ilam, Iran: a retrospective cohort study}, abstract ={Since December 2019, coinciding with the outbreak of COIVD-19 in China and its spread to all countries, the greatest post-World War II health crisis and human society challenge has severely affected health systems, the global economy, and governments. [1] As previous priorities and routine activities in most areas have ceased and extensive efforts and investments have been made to prevent, diagnose and treat the disease, reduce the incidence rate, reduce the number of critically ill patients in need of intensive care and finally reduce the mortality rate [2]. Despite this unprecedented effort, various diagnostic and therapeutic aspects of the proposed and in use have been accompanied by many challenges and doubts so far [3]. Therefore, reducing the limitations and gaps in existing knowledge is the main priority and focus of studies in the field of medical sciences according to the encouragement of the World Health Organization. [4] According to studies, many factors can affect the prognosis of coronary heart disease and mortality. Most of the information on the epidemiological and laboratory factors of COVID-19 is insufficient and questionable, and there is insufficient evidence and evidence for its use. Recognizing the importance of each of the indicators related to mortality from disease, using efficient output models can in the process of treatment and better care, management of scarce resources during the peak of the disease, including prioritization of special beds and hospital beds, human resource management due to limitations Professional human resources, increasing the reliability of patients at lower risk for home care, appropriate planning for drug allocation and possible vaccines if used in the future. Therefore, the aim of this study was to explain the role of epidemiological and laboratory risk factors on the mortality of coronary patients using the artificial neural network model. Methods: The present study is a retrospective cohort study in which the demographic and laboratory characteristics of patients who referred from the onset of coronary heart disease (March 1) to July 1 with a definitive diagnosis of COVID-19 and improved or died were studied. they enter. Demographic, clinical and laboratory variables are then analyzed using the artificial network model to identify risk factors associated with patient mortality. After approving the plan and getting the code of ethics, information is collected from the files or the registry system. After completing the information through previous data, reviewing the files if necessary and contacting patients and their families, analysis and analysis using MATLAB software and effective factors in mortality, mediating variables, and the share of each The factor will be identified in explaining the variance of the dependent variable to determine the importance of each factor and ...... and the results will be presented in the form of analysis, table and graph.}, Keywords = {COVID_19 , Artificial neural networks , mortality}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1087-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1087-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Mohamadpour, Shahram and Abbasi, Naser}, title = {The Effect of forced exercise on the Hippocampus of Mice after Induced Ischemia Reperfusion}, abstract ={one of the most important causes of ischemia is stroke, which is the third leading cause of death in Western countries after myocardial infarction and cancer. Dies and 5 million people become permanently disabled. (2) Cerebral ischemia is a decrease in the amount of cerebral metabolites due to decreased blood flow, which leads to a decrease in oxygen storage and consequently the death of brain tissue or stroke. (3) Cerebral ischemia leads to movement, sensory and Vision, speech disorders, behavioral disorders, especially spatial learning disabilities. The effects of reperfusion are the result of the inflammatory function of the damaged tissue, which releases white blood cells, inflammatory factors such as interleukins, and free radicals into the damaged tissue as the blood returns, causing oxidative stress. (5) that certain areas of the brain and certain types of neurons, including pyramidal neurons in the CA1 region of the hippocampus and striatum, are more sensitive to cerebral ischemia. (6, 7) The hippocampus is the part of the brain that is located in the lateral ventricular floor of the temporal lobe and has specific areas called the dentate gyrus and the ammonia horn, which consists of three parts: CA1, CA2, CA3, and the neurons in each area. The hippocampus has unique biophysical properties, intracellular environment, and receptors (8). This has been implicated in the formation of new memory and the processing of spatial information (9), and it has been shown that differentiation of neuroblasts and production of new neurons in mammals begins in the two subgranular regions of the hippocampus and the ventricle of the olfactory bulb in the brain. 10, 11). The hippocampus is also supplied by the anterior choroidal artery, which is a branch of the internal carotid artery. , Epilepsy, stroke, ischemia and especially brain trauma. (12) Extensive research has been conducted to find an effective drug to reduce the damage caused by ischemia and restoration of blood flow (13), and much research has been done on stimulating neurogenesis through enriched environments, physical activity, and memory-related tasks. And learning, the use of therapeutic cells of different origins and antioxidants. Over the past 20 years, animal studies have shown beneficial effects of physical exercise on cerebral ischemia, including increased survival, reduced neurological defects, improvement in blood-brain barrier defects, and blood vessel integrity (14). Biochemical activity of the hippocampus following exercise strengthens memory (15) and it has been shown that physical activity has a neuroprotective effect against hippocampal damage that damages memory, as well as increasing the expression of neuronal growth factors such as insulin-like growth factor NGF and growth factors. Fibroblasts and vascular growth factor (16, 17) Other studies have shown that exercise reduces neuronal function as well as stroke volume in rats. (18) and reduces inflammatory damage by reducing the expression of inflammatory mediators as well as reducing leukocyte accumulation. [19] It also improves short-term memory and spatial memory by increasing neuron production as well as reducing apoptosis in the hippocampus. 20) According to many studies on reducing the damage to the hippocampus after ischemia-reperfusion induction, the effect of exercise neurogenesis on the hippocampus before ischemia has also been proven, but so far in the effect of swimming exercise on the hippocampus. After induction of ischemia-reperfusion, no comprehensive research has been done (therapeutic effect of exercise). Therefore, we investigate the effect of swimming exercise on mice hippocampus after ischemia-reperfusion induction}, Keywords = {Reperfusion ischemia, hippocampus, swimming exercise}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1922-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1922-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Mirzaei, Asad and alikhani, maryam and Pakzad, Iraj}, title = {Genetic variability between Trichomonas vaginalis isolates and correlation with clinical presentation in patients refferd to Ilam hospitals}, abstract ={}, Keywords = {}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1888-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1888-en.DOCX}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Moayeri, Ardeshir and Abbasi, Naser and Ramz, khoiou}, title = {Effect of combination Aloe vera and Vitis vinifera leave Extract on the Healing of Second-degree burn Wounds in rats}, abstract ={Background and objective: In different societies, burns are one of factors wasting capital and time of countries around the word, recovery of which incurs huge expenditures and has a slow process as well as some side effects and disabilities which make such patients prone to be damaged mentally and psychologically. The aim of work was to evaluate the effects of Aloe vera and Vitis vinifera extract combination on wound healing second degree burn’s in male wistar rat and compared with SSD and other groups. Method:  72 male wistar rats were divided into 12 equal groups. The burn was made on the back of all rats, firstly dorsum of each rat was shaved and then the area was burned in order to 10 mm in diameter of second degree burn injury. The burned areas in the groups included: were not treated with any healing agent (control) and were treated topically with eucerin, treated with silver sulfadiazine ، covered with %5 ، %1 ، %1.5 ،%2 Vitis vinifera extract in eucerin base cream and, covered with %5 ، %1، %1.5 %2 Aloe vera extract in eucerin base cream and with aloe vera plus Vitis vinifera extract twice a day respectively. 21 days later the rats were sacrificed and burned skin tissue samples were collected from the rats for histopathological examination. They were evaluated parameters to be considered for review included the number of hair follicles, sebaceous glands of angiogenesis, inflammation, acute (severe infiltration of neutrophils) and the formation of an epithelial layer.  }, Keywords = {SSD - Aloe vera- Vitis vinifera- Second-degree burn}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1861-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1861-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Mami, Sanaz and Kafashian, Mohamadreza and Davoodian, Abdollah and Ahmadi, Alireza and Falahivastani, Zahr}, title = {Measurement of LI-18, IL-10 and interferon gamma in the serum of people with COVID-19 in Imam Khomeini Hospital, Ilam}, abstract ={}, Keywords = {IL-10.1L-18.IFN-G.COVID-19}, volume = {5}, Number = {1}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-924-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-924-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Jalilian, Mohsen and Mirzaei, Amin and Kakaei, Hojatollah and Bakhtiyari, Salar and Mazloomi, Sajad and Nourmoradi, Heshmatolah}, title = {Investigation of health information-seeking behavior related to covid-19 disease in young people of Ilam province}, abstract ={Investigation of health information-seeking behavior related to covid-19 disease in young people of Ilam province  }, Keywords = {covid-19, health information-seeking behaviors, youth}, volume = {5}, Number = {2}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-916-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-916-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {sarokhani, m}, title = {Prevalence of depression in Iranian nurses. Systematic review and meta-analysis}, abstract ={Depression is a debilitating disease and one of the common and serious disorders that undermines a person's mental and physical health and imposes a heavy burden on society (Mahmoudi, Menti, 2017, p. 29). In fact, it is a pathological feeling of sadness, which is accompanied by some degree of stagnation of reactions. Humility (2006, quoted by Ghasemnejad, 2019). And it is considered one of the 4 major diseases in the world and the most common cause of disability caused by the disease. The incidence of depression at a young age is associated with a severe drop in social and occupational performance as well as academic performance (Arshadi Kia, Shajari, Tayibi, 2009, p. 349). Today, inappropriate emotional reactions such as stress, anxiety and depression are considered as a well-known and integral part of modern nursing, which causes many problems for nurses and patients. (Khamsa, Rouhi, Ebadi et al., 1388, p. 13). The wide scope of the activities of nurses and the interdisciplinary nature of this profession cause occupational trauma in nurses and cause mood changes, especially depression in them (Dehghani, Zol-Adl, Balandparvaz et al., 2017, p. 24). The purpose of this study is to estimate the prevalence of depression in Iranian nurses by systematic review and meta-analysis.}, Keywords = {depression, nurses, Systematic review and meta-analysis}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2028-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2028-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Sayehmiri, Kourosh}, title = {A survey on the status of the quality of life of drug employed people in Iran: a study of systematic review and meta-analysis}, abstract ={The quality of work life as a philosophy is a set of principles that believe that human resources are the most important and reliable resources in organizations. who are responsible and capable of valuable participation and should be treated with dignity and respect. And it is a comprehensive structure that includes well-being related to individual job and to some extent valuable work experience, doing work without stress and other personal negative consequences.(1) Unfavorable quality of work life, which arises under the influence of inappropriate and incompatible work with humans, creates unbalanced psychological and social conditions in the employees of an organization (2). The quality of work life is a combination of work environment variables that are effective in promoting satisfaction, attracting and maintaining and improving the quality of employee services (3).}, Keywords = {Quality of life, workers, meta-analysis}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2081-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2081-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Mirzaei, Amin and Pouresmaeili, Fatemeh and jalilian, mohse}, title = {The effectiveness of educational intervention based on Health Belief Model on mothers behaviors about complementary feeding of 6-18 months infants}, abstract ={Background and aim: Complementary feeding (CF) plays a key role in the development and prevention of malnutrition in infants under two years of age. The purpose of this study was to determine the effectiveness of educational intervention based on Health Belief Model (HBM) on mothers' behavior on CF of 6-18 months old infants in Andimeshk. Materials and methods: The present study was conducted in two stages. In the first stage, a descriptive study was conducted with 270 mothers with 6-18 month old infants referred to six health centers that were selected randomly and included in the study. The results of the descriptive study were analyzed for the needs assessment of educational intervention. In the second stage, based on the results of the descriptive study, appropriate educational intervention was designed and implemented. Educational intervention was conducted in two intervention (n=32) and control (n=35) groups for three weeks. Data were collected by a 53-item questionnaire in two stages before and one month after the intervention and were analyzed using SPSS software and descriptive statistics, Pearson correlation, multiple linear regression, one-way ANOVA, chi-square, independent samples t-test and paired samples t-test.  }, Keywords = {Complementary Feeding, Infants, Health Belief Model, Educational Intervention}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2062-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2062-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Ghafourian, Sobhan and aboualigaledari, elham and norozi, Massoumeh and Maleki, Abbas}, title = {Antitoxin Toxin System as an antimicrobial target in Clinical Acinetobacter baumannii}, abstract ={Introduction:Acinetobacter baumannii is a gram-negative bacterium that is commonly associated with multi drug resistance of opportunistic infections. This bacterium can cause a wide range of infections including bacteremia, pneumonia, meningitis, urinary tract infections and wound infection in susceptible patients. Toxin-antitoxin (TA) system is a regulated system that could be used for new antimicrobial targets. Therefore, in this study, the antitoxin-toxin system was evaluated as an antimicrobial target in clinicalisolates of A.baumannii Material and method: Eighty clinical isolates were collected from ICU and burn wards of Ilam hospitals during the year 2018 and were confirmed by biochemical and molecular methods of as Acinetobacter baumannii. Antibiotic resistance was performed by disfiguring disk on all isolates. The presence of MazE, MazF and HighA antitoxin toxin systems was performed by PCR method and expression of these systems by RT-PCR method. Results: Resistance to antibiotics were detected for kanamycin (81.3%), tetracycline (48.8%), amikacin (51.3%), gentamycin (48.8%), tobramycin (28.8%), doxycycline (8.28%), and minocycline (7.5%). The frequency of toxin and antitoxin genes of MazE, MazF,HighA, and HighBin isolates was 62.5%, 46.3%, 38.8%, and 37.2% respectively. The frequency of plasmidTA systemesof MazE, MazF, HighA, and HighB in all isolates was 43.8%, 33.8%, 23.8%, and 21.0% respectively. The expression of the MazEF locus function was confirmed in all isolates by RT-PCR Conclusion: Our findings indicate that there is a high antibiotic resistance in the Acinetobacter baumannii isolates. In this study, the high prevalence of the MazEF toxin-antitoxin system and the expression of this system in isolates has been proven. Therefore, the deactivation of the MazEF loci could be used as a new antimicrobial strategy in the treatment of resistant infections caused by this bacterium.}, Keywords = {A.baumannii, Antibiotic resistance, Toxin-antitoxin, MazEF, PCR, RT-}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2029-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2029-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Bagheri, Maryam and Salari, Sajad and oshnokhah, mahi}, title = {Assessment of Oxidant/Antioxidant Status and Nerve Growth Factor in Suicide Attempters in Ilam city}, abstract ={Considering the high rate of suicide in Ilam province compared to other regions of the country, it seems that investigations beyond descriptive and analytical studies are needed. Today, biological studies are one of the tools used in the diagnosis of various diseases, especially psychiatric diseases. The introduction of various biological factors in the study of the occurrence of diseases not only helps to identify them, but can also provide new solutions for their prevention and treatment. Based on this, we decided to investigate the status of oxidants, antioxidants, and nerve growth factor in suicidal individuals referred to Shahid Mostafa Hospital in Ilam city.}, Keywords = {Suicide attempt, oxidative stress, malondialdehyde}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2104-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2104-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Jalilian, Mohsen and mansori, soraya and Aivazi, Ali-Ashraf}, title = {The effect of educational intervention on preventive behaviors of Crimean-Congo fever in rural women of Malekshahi County}, abstract ={}, Keywords = {Crimean-Congo Hemorrhagic Fever (CCHF)}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-441-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-441-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {tahmasebighorabi, samaneh and AbedzadehZavareh, Mohamad Sadegh and Jalilian, Mohsen and Sadeghifar, Jamil}, title = {Investigating the effect of education based on intervention mapping model on health promoting behaviors among staff of Ilam university of medical science}, abstract ={Lifestyle is the normal and usual daily activity of people that affects people's health. Employees should be aware of correct health behaviors so that they can use them to improve their health and quality of life.}, Keywords = {health promoting behaviors, intervention mapping, staff}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-372-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-372-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Sayehmiri, Kourosh and mamashli, khadijeh and Valizadeh, Reza and Khorshidi, Ali and Rostamkhani, Marzieh and Yadegari, Noorollah and Mohamadian, Fathola and Aivazi, Ali-Ashraf and Kikhavani, Sattar}, title = {A Registration system for suicide Attempts in Ilam Province}, abstract ={}, Keywords = {Registration system, suicide Attempts, Ilam Province}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-473-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-473-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {GhaneiAlvar, Hori and Abbasi, Naser and gholami, milad and Karimi, Elaheh}, title = {Synthesis and study of the antibacterial and fungal effect of chitosan bead hydrogels cross-linked with double-layered hydroxides containing iron nanoparticles}, abstract ={}, Keywords = {Iron nanoparticle, double-layered hydroxides, antibacterial properties}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1098-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1098-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Maleki, Abbas and khoshnood, saeed and Sadeghifard, Nourkhoda and Hassankaviar, Vahab and hadadi, mohammad hossien and Valadbeigi, Hasan and karamolahi, somaaye and hashemian, marzieh and omidi, nazani}, title = {Prevalence of Tigecycline -resistant strains in clinical isolates of Acinetobacter baumannii and evaluation of their genetic association using multilocus sequence typing (MLST), MLVA and Multiplex PCR}, abstract ={Acinetobacteria are non-fermenting gram-negative coccobacilli that have been identified as one of the leading causes of nosocomial infections over the last three decades. The mortality rate from this bacterium is also relatively high, so that in a study conducted in 2010, out of 146 patients with Multi-drug resistant Acinetobacter pneumoniae (MDR), 23 (15.8) of them died. The cyclin is the first FDA-approved antibiotic for glycine glycine antibiotics. This antibiotic has significant potency against gram-negative and gram-positive bacteria and anaerobic bacteria including multidrug-resistant strains (MDRs). The resistance of Acinetobacter baumannii to this antibiotic is not very high, but today we see a gradual increase in resistance to this antibiotic, which makes it difficult to treat these infections. One of the most important and widely used methods for molecular typing and clonal relationship evaluation of bacterial isolates is the Multilocus sequence typing (MLST) technique. Given the above and the need to understand the mechanisms of resistance and profiles related to ticycline resistance, we decided to conduct a study entitled: Prevalence of ticycline-resistant strains in clinical isolates of Acinetobacter baumannii and evaluation of their genetic relationship using Perform MLST, MLVA and Multiplex PCR sequencing. This method is one of the high sensitivity molecular methods and is used today to study the typing pattern in different bacteria. In recent years, with the introduction and development of molecular typing methods such as Variable number tandem repeat and Multiplex PCR, significant genetic diversity has been observed among Acinetobacter baumannii strains. In the Multiple loci VNTR analysis (MLVA) technique, by selecting different loci in terms of each repeating unit size and longitudinal polymorphism, the ability to differentiate between strains is provided.}, Keywords = {acinetobacter baumannii, antibiotic resistance, MLVA , MLST}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1318-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1318-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Shams, Morteza and Basati, Gholam and Majidiani, Hamidreza and Asghari, Ali and Nourmohammadi, Hassan and Asghari, Ali}, title = {Review of anticancer drug compounds: a systematic review of anti-tumor activity of parasite-derived compounds}, abstract ={Parasites are a group of micro-organisms that have evolved enough with at least one host larger than themselves to complete their evolution and meet nutritional and reproductive needs.They are constantly exploring and confronting the host's immune system to ensure their survival and complete their life cycle.In this context, a variety of molecules are expressed and used both by the host and by the invading parasite to confront each other. With the increasing progress of biochemical methods and molecular biology, it has been determined that some of these molecules, in addition to their toxic or harmful role, can be immune-modulating roles, and therefore, they may be used for the possible treatment of various immune-mediated disorders or atopic diseases. According to the hypothesis of the World Health Organization, which was proposed in 1989, exposure to infectious agents during childhood has an inverse correlation with the occurrence of allergic diseases in the later years of a person's life, similar to what we see in developed countries. This issue was then extended to inflammatory diseases, type 1 diabetes and cancer.Regarding parasites, recently, in addition to the carcinogenic role of some of them such as Schistosoma hematobium and Trichomonas vaginalis, studies have been published to show the anti-cancer properties of some compounds derived from parasites.Therefore, the purpose of the present systematic review is to systematically collect these articles and extract valuable data from them in order to advance future approaches and also identify possible weaknesses.}, Keywords = {Parasite, Medicinal compounds, A systematic review, Anti-tumor}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1249-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1249-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {GhaneiAlvar, Hori and Abbasi, Naser and Hadadi, MOHAMMAD HOSEIN}, title = {Engineered Chitosan Nano-film with Polyunsaturated Fatty Acids and Mesenchymal Stem Cells for Burn Wound Healing with Anti-Biofilm Properties in Rat Animal Model.}, abstract ={زخم های سوختگی به شدت مخرب و ناتوان کننده هستند و به دلیل درگیری بسیاری از ارگانهای بدن، شیوع مرگ و میر بالایی دارند. طبق اعلام سازمان بهداشت جهانی (WHO) سالیانه تعداد 265000 بر اثر زخم سوختگی می میرند. با توجه به پیچیدگی زخم سوختگی و شیوع بالای عفونت در این افراد، علم پزشکی نیاز به روشهای جدید، با اثر بخشی بالا، ایمن و کم هزینه جهت جلوگیری از عفونت زخم، افزایش حساسیت آنتی بیوتیکی و افزایش ترمیم کنندگی بافت آسیب دیده دارد. پوست اولین ارگان درگیر شده در زخم سوختگی می باشد که بیشترین عفونت باکتریایی با ظهور بیوفیلم باکتریایی را تجربه می کند. کیتوزان به عنوان یک ماده ایمن و زیست تخریب پذیر در ارسال دارو و ژن درمانی استفاده می شود. علاوه بر این کیتوزان به عنوان پوشش هموستاتیک  و بانداژ و یک عامل پیشگیری کننده از عفونت باکتریایی و قارچی در زخم سوختگی مورد استفاده قرار می گیرد. ریز لایه­ها یکی از انواع ریز ساختارها کاربردی در درمان زخم سوختگی می باشند. ریز ساختارهای تولید شده از پلی ساکاریدهایی مانند کیتوزان دارای نفوذپذیری  بالا در محیط آبی می باشند. به دلیل انعطاف پذیری، نازک بودن و شفاف بودن ریز لایه های کیتوزان/آلژینات در سازه های پوششی برای افزایش ترمیم زخم در مقایسه با بانداژهای رایج جهت کاهش طول درمان و مهار تشکیل اسکار مورد استفاده قرار می گیرند. مقاومت ریز لایه به محیط آبی با استفاده از لیپید هایی مانند اسید های چرب غیر اشباع امگا- 3 و- 6 افزایش می یابد. کاهش کشش سطحی ترکیبات ریز لایه باعث کاهش فضای نزدیک شونده بین دوزنجیره پلیمری می شود. ایکوزاپنتانوئیک اسید (EPA) و دکوزاهگزانوئیک اسید (DHA) از مهمترین امگا -3 های استخراج شده از روغن ماهی می باشند که به کارگیری آنها در سازه ریز لایه منجر به کاهش کشش سطحی و کاهش گذر بخار آب خواهد شد. اسید های چرب غیراشباع چندگانه دارای خصوصیات درمانی قابل توجهی مانند ضد التهاب، ضد میکروبی و همچنین ضد بیوفیلم در عفونت زخم هستند. دو ترکیب مهم DHA و EPA (مشتق امگا-3) دارای خاصیت ضد التهابی با کاهش بیان فاکتور رونویسی NF-kB و TNF-alpha و افزایش بیان NOS و IL-1 beta هستند. افزایش سطح لیپید های اشباع نشده در غشای فاگوسیت ها باعث افزایش عملکرد فاگوسیتوز در آنها می شود. مطالعات آزمایشگاهی و بالینی نشان می دهد که DHA و EPA به صورت تک و یا مجتمع با سایر آنتی بیوتیک ها علاوه بر ایجاد شرایط ضد التهابی دارای خصوصیات آنتی میکروبی برعلیه باکتری های گرم منفی و گرم مثبت هستند. مشتقات لینولئیک اسید (DHA و EPA) از خانواده امگا-3 باعث مرگ گونه پلاسمودیوم، استافیلوکوکوس اورئوس پاتوژنز ، باسیلوس سرئوس ، هلیکو باکتر پیلوری و باکتری بورخولدریا سپاسیا (Burkholderia cepacia) شده و همچنین دارای خصوصیات آنتی ویروسی (از تکثیر ویروس جلوگیری می کند) و ضد قارچی می باشد. اسید های چرب غیر اشباع با زنجیره بلند (EPA و DHA) علاوه بر خاصیت متوقف کننده رشد باکتری دارای خاصیت ضد بیوفیلم نیز هستند.  سلول درمانی با استفاده از سلولهای بنیادی مزانشیمی، کراتینوسیت و همچنین دیگر سلولها مانند فیبروبلاست های پوست جهت درمان زخم سوختگی بسیار کارآمد است. یکی از مهمترین ویژگی های سلولهای بنیادی مزانشیمال خاصیت القاکنندگی مهار پاسخ ایمنی می باشد که در زخم سوختگی گزارش شده است. با توجه به اینکه برای درمان زخم سوختگی نیاز به درمانی است که پوشش بافتی شفاف با گذر بخار آب سطحی کم در زخم ، ریز لایه ساخته شده از کیتوزان و آلژینات یک کاندید تایید شده برای پوشش دادن عفونت زخم سوختگی هستند که می­توان با استفاده از اسیدهای چرب غیر اشباع کشش سطحی آن را کاهش داد. به دلیل حضور عفونت باکتریایی در ناحیه زخم سوختگی معمولاً یک التهاب شدید در ناحیه زخم ایجاد می­شود  لذا با توجه به خاصیت ضد باکتریایی کیتوزان و همچنین خاصیت ضد باکتریایی و بیوفیلم اسیدهای چرب غیر اشباع امگا-3 می­توان ریز لایه­ای از کیتوزان را طراحی کرد که حاوی مشتقات امگا-3 و سلول بنیادی مزانشیمی باشد تا بتواند ضمن مهار التهاب و تشکیل عفونت و بیوفیلم با افزایش رگ زایی و بازسازی زخم مدت ترمیم زخم را هم کاهش دهد، در این مطالعه سلول­های بنیادی مزانشیمی جدا شده از خون بند ناف مورد استفاده قرار میگیرد. تا کنون هیچ مطالعه­ای در ارتباط با  درمان زخم سوختگی با ریز لایه مشابه همراه با اسید چرب غیر اشباع جهت مهار عفونت زخم باکتریایی همراه با بیوفیلم چه به صورت تنها و چه همراه با سلول بنیادی انجام نشده است.}, Keywords = {wound-stem cell-Chitosan-}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-753-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-753-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Rashidi, Fatemeh and Azadi, Arm}, title = {Evaluation the relationship between students\' attitudes toward Ilam University of Medical Sciences towards the elderly and the desire of students to health care of them in the health centerS of ilam city in 2021}, abstract ={Anthropologists and sociologists consider population aging to be the most important phenomenon of the present age [2]. According to the World Health Organization, by 2025 the population of the elderly will reach more than 800 million [5]. Also, according to another report from this organization, a high percentage of the need to use health services compared to the total population is related to the elderly. The need for comprehensive attention to the elderly is due to the fact that these people have many health problems and are the main consumers of health services [3]. The significant increase in the elderly population has posed many challenges to health policymakers. [4] One of the most important challenges is maintaining the quality of health care for the elderly. There are various factors involved in providing quality services to the elderly, but one of these factors is the attitude of health care providers to the elderly and the phenomenon of aging [7]. Therefore, the main purpose and necessity of this study is to investigate the attitudes of students of Ilam University of Medical Sciences and their willingness to work with the elderly because their field of work in the future may be directly related to the provision of services and health care to the elderly.}, Keywords = {attitude, elderly, students of medical university}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1386-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1386-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Sahebi, Ali and Jamshidbeigi, Yousof and Mohammadi, Sar}, title = {Investigating the performance the hospital response to a fire incident through a case study in Ilam}, abstract ={Hospitals may be completely affected by fire and forced to evacuate to reduce potential damage. Non-transferability of a significant portion of medical equipment, problems with the relocation of critically ill patients with special conditions, patient safety issues during the transfer process, and challenges related to evacuation within a limited period of time after the declaration of a state of emergency These are issues that hospital managers face. Hospitals are exposed to fire hazards due to the use of flammable materials and in many cases are forced to evacuate in an emergency. The purpose of emergency evacuation is to increase the number of evacuated people in the shortest possible time, which requires preparedness and The purpose of this study is to determine and analyze the response of Ayatollah Taleghani Hospital in Ilam to fire and the results of this study can be the level of preparedness of hospitals and managers to respond to fire and emergency evacuation. Increase.}, Keywords = {fire, hospital, incident}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1332-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1332-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Jamshidbeigi, Yousof and Mozafari, Aliashraf and Kalvandi, Gholamreza and Kafashian, Mohamadreza and Kenarkoohi, Azra and Nazari, Ali and Ahmadi, Iraj}, title = {1. Title: Determine the consequences of delay in referring to the hospital in patients with Covid 19 in Shahid Mostafa Khomeini Hospital of Ilam Province}, abstract ={Coronavirus یکی از مهمترین عوامل بیماری زا است که در درجه اول سیستم تنفسی انسان را هدف قرار می‌دهد. شیوع قبلی کروناویروس ها (CoVs) شامل سندرم تنفسی حاد (SARS)-CoV و سندرم تنفسی خاورمیانه (MERS)-CoV بود  که از قبل به طرز موثری به عنوان عامل هایی شناخته می شدند که یک تهدید بزرگ برای سلامت عمومی جامعه هستند.[1] در اواسط دسامبر سال 2019 ، یک دسته از بیماران با تشخیص اولیه پنومونی با علت ناشناخته در بیمارستان ها بستری شدند. این افراد به صورت اپیدمیولوژیکی به یک بازار محصولات دریایی ووهان چین مرتبط بودند. تعیین توالی از نمونه های دستگاه تنفسی تحتانی ، یک کروناویروس جدید را نشان داد که کروناویروس 2019 (2019-nCoV) نامگذاری شد. [2] ظرف 8 هفته، این بیماری ویروسی در سطح جهانی گسترش یافته است به حدی که سازمان بهداشت جهانی (WHO) آن را در 11 مارس 2020  به عنوان یک بیماری همه گیر جهانی اعلام کرد که تا 14 مارس 2020 علاوه بر چین، این پاندمی بیش از 150 کشور را درگیر کرد.  [3]}, Keywords = {delay in referring, Consequences, Covid 19}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1175-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1175-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Sadeghifar, Jamil and nargesi, shahin and dolatshahi, zeinab}, title = {Economic Evaluation of Diagnostic Methods of Covid-19: A Systematic Review}, abstract ={The new coronavirus, known as SARS, causes severe respiratory illness. The incubation period is about 6 days. Early symptoms include chills, lethargy, dizziness, cough and sore throat, and shortness of breath appears after a few days. Many patients have abnormal chest radiographs. Some cases progress rapidly to acute respiratory distress and require respiratory support (artificial respiration). Death is the result of progressive respiratory failure, which is about 10% higher in middle-aged mortality. Laboratory tests are not usually performed to diagnose coronavirus infections except in the case of SARS. The available methods for coronavirus detection include SARS-Cov, detection of RNA virus genome in the respiratory tract and fecal samples by RT-PCR. Isolation of coronaviruses is difficult and requires (biosafety level 3) conditions for SARS-Cov. Economic evaluation of coronavirus diagnostic tests can play an important role in informing decision makers about reimbursement of care costs, pricing of medical interventions, providing cost-effective clinical guidelines on the use of diagnostic methods, providing targeted interventions, and producing scientific evidence. Have a policy to make decisions and ultimately lead to cost management, efficiency and optimal allocation of limited financial resources of the health system in the field of viral and infectious diseases economics. . Therefore, the present study systematically reviews and focuses on patients with coronary artery to evaluate the diagnostic tests of this disease.}, Keywords = {Economic evaluation, cost effectiveness, Covid-19, diagnostic tests, systematic review}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1447-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1447-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Zakariaee, Seyed Salman and hossini, mogtab}, title = {Portable unite for measuring body fluid components}, abstract ={Portable unite for measuring body fluid components}, Keywords = {Portable unite for measuring body fluid components}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1622-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1622-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Shanbehzadeh, Mostafa and Kafashian, Mohamadrez}, title = {Design and development of Computerized Decision Support System (CDSS) for COVID-19 diagnosis}, abstract ={Coronavirus disease 2019 (COVID-19) has widely spread all over the world since December2019. This pandemic poses a great threat and challenge to global health and economy. The COVID-19 diagnosis and treatment is very complex, because of its unknown many characteristics. Thus it is crucial to have a framework for an early of its prediction. In this regard, Machines Learning (ML) could be the crucial to extracting high-quality predictive models and concealed patterns from mining of huge raw datasets. Purpose: At this juncture, we aimed to apply different ML models to discover correlations in COVID-19 data that could help improving prediction rate. Additionally, their potential was evaluated to find the best classifier which gives better accuracy. Material and Methods: The dataset of Talleghani hospital, COVID-19 focal center affiliated to Abadan University of Medical Sciences have been taken into consideration. ML algorithms such as Naïve Bayesian (NB), Bayesian Net (BN), Random Forest (RF), Multilayer Perceptron ( MLP ), K-star, C4.5, and Support Vector Machine ( SVM ) were developed. Then the recital of selected ML models was assessed by comparison of some performance indices such as accuracy, sensitivity, specificity, precision, F-score, and Receiver Operating Characteristic (ROC).}, Keywords = {Data mining, COVID-19, machine learning, decision suppotrt}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1252-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1252-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Ahmadi, Iraj and Maleki, Maryam and Kafashian, Mohamadreza and falahi, shahab and Kenarkoohi, Azra and GhaneiAlvar, Hori and estabarghnia, Hmideh and HassaniAzad, Mehdi and ghanbarnejad, Amin and KazemiJahromi, Mitr}, title = {Study of Comparative changes in blood cortisol concentration and ACTH in COVID-19 patients admitted to Shahid Mostafa Khomeini Hospital in Ilam and Shahid Mohammadi Hospital in Bandar Abbas}, abstract ={Physiological stress caused by diseases increases cortisol by acting on the hypothalamic-pituitary-adrenal axis. Elevated cortisol is one of the most important mechanisms for overcoming stress, which triggers adaptive mechanisms in the cardiovascular system, metabolism, and immune system. The effect of COVID-19 on blood cortisol is unclear. SARS-CoV-2 appears to initiate immunological responses that theoretically increase morbidity and mortality, possibly due to cortisol secretion failure. Not many studies have been done on this. Whether this trend may be related to the pathophysiology of COVID-19 is not yet known, and there is insufficient evidence of adrenal changes in patients dying from SARS-CoV-2, but in patients with SARS-CoV, monocyte infiltration has been observed. There are lymphocytes and focal necrosis in the adrenal glands. Venous vasculitis has also been reported in the medulla. Due to the similarities between the two viruses, these adrenal disorders may also be seen in COVID 19 disease patients.}, Keywords = {cortisol , ACTH ,COVID 19}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1238-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1238-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Mirzaei, Amin and Zinivandmoghadam, leila and Jalilian, Mohse}, title = {The effectiveness of theory-based educational intervention on fruit and vegetable consumption of high school girl students in Ilam city}, abstract ={Background and aim: Consumption of appropriate amounts of fruits and vegetables in the daily diet is one of the important methods of disease prevention and health promotion, especially in adolescents. The aim of this study is to determine the impact of educational intervention based on Social Cognitive Theory on fruits and vegetables intake in female high school students in Ilam. Materials and methods: the present study was conducted in two stages. In the first stage, a descriptive study was conducted with the participation of 332 female high school students from 5 schools in Ilam who were selected by random sampling and entered into the study. The results of the descriptive study were analyzed to determine the most important predictor of behavior for the intervention.  The educational intervention was performed with the participation of two groups of intervention (80 samples) and control (80 samples) for 4 weeks in the form of 5 educational sessions. Data were collected using a 54-item questionnaire in two stages before and three months after the educational intervention Data were analyzed using descriptive statistics, Pearson correlation, and multiple linear regression, one-way ANOVA, independent t-test and paired t-test by SPSS 19 software.  }, Keywords = {Fruits and vegetables, Adolescent, Social cognitive theory, Educational intervention}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2061-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2061-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {shiri, samira and Sayehmiri, Kourosh}, title = {Comparison of the growth hormone, oxandrolone, letrozole and anastrozole’s impact on the height increase in children and adolescents with idiopathic short stature (ISS): a systematic review and meta-analysis}, abstract ={Background: Short children face many problems throughout their lives. Consumption of growth hormone and the drugs such as Letrozole, Oxandrolone, and Anastrozole can increase the growth of children and adolescents. There is not an overall estimate of the effects of Letrozole, Oxandrolone, and Anastrozole on the growth of children and adolescents with Idiopathic Short Stature (ISS). There are different estimates of the effect of growth hormone and the drugs Letrozole, Oxandrolone, and Anastrozole on growth in children and adolescents with Idiopathic Short Stature. Therefore, the aim of this study was to compare the efficacy of growth hormone, Letrozole, Oxandrolone, Anastrozole, and a combination of growth hormone and aromatase inhibitors on height gain in children and adolescents with idiopathic short stature using meta-analysis method. Methods: Search was done in databases such as; Scopus, Web of Science(ISI), and PubMed using keywords: Idiopathic, Short Stature, Body Height, Aromatase Inhibitors, Growth hormone, Letrozole, Oxandrolone, Anastrozole. Randomized clinical trial studies ,that have investigated the efficacy of growth hormone and aromatase inhibitors on height gain in children and adolescents with short stature, were selected. Height standard deviation score (HSDS) before intervention and after treatment has been used to measure the rate of height increase in various studies. This study was written based on the PRISMA checklist and the heterogeneity of this study was evaluated using the Q statistic and I2 index. Results: Height increase index (HSDS) was obtained with the use of growth hormone combined with one of the aromatase inhibitors (0.38-3.58=95%CI) (SMD=0.98), with the use of growth hormone (0.62-1.14=95%CI) (SMD=0.88), with the use of Letrozole (0.51-16.51=95%CI) (SMD=0.83), with the use of Oxandrolone (0.99-0.99=95%CI) (SMD=0.56), and with the use of Anastrozole (0.00-0.63=95%CI) (SMD=0.31), which shows that all these drugs have a significant effect on height increase. (P<0.05) Conclusion: Although the effect of growth hormone on height increase was greater than that of aromatase inhibitors, but according to our results, adding an aromatase inhibitor to growth hormone can increase the effectiveness of it.}, Keywords = {anastrozole, aromatase inhibitors, body height, growth hormone, idiopathic, letrozole, oxandrolone, short stature}, volume = {5}, Number = {3}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2094-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2094-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2022} } @article{ author = {Abdi, Jahangir}, title = {Genotyping of giardia lamblia and its relationship to clinical sign in patients with giardiasis in Ilam Province}, abstract ={Giardia lamblia has proved to be the most common intestinal protozoan parasite in humans that causes giardiasis. Given the high mutations in the genome of this parasite, the present study was conducted to determine the prevalence of Giardia lamblia subtypes and their relationship with clinical symptoms in patients who appear to have giardiasis. In 69 stool specimens with an appropriate number of giardia cysts, the DNA was first purified, and the genotype was then determined based on the glutamate dehydrogenase (gdh) gene sequence using PCR-RFLP. Data were collected on the clinical symptoms of the patients through a questionnaire, and their relationship with molecular results was studied. Four samples (5.8%) were found to be of subtype AI, 51 (73.9%) of subtype AII and 14 (20.3 %) of subtype BIII. No BIV subtype was found in the present study. A correlation was observed between Giardia lamblia genotypes (AI, AII and BIII) and abdominal pain. All of the people 11/30/22, 3:08 PM Giardia Lamblia Subtypes and Their Relationship with Clinical Symptoms in Patients with Giardiasis - PubMed https://pubmed.ncbi.nlm.nih.gov/30868967/ 2/2 (100%) who had the AI genotype (i.e. the zoonosis subtype) had been losing weight. There was a significant correlation between weight loss and the AI subtype. All of the people (100%) infected with the BIII genotype experienced diarrhea, and this genotype was found to be associated with diarrhea. The present study found abdominal pain to be the most common symptom of giardiasis in Ilam province. Moreover, humans were found to be the main reservoir for giardia lamblia, although zoonosis subtypes such as AI and BIII still exist in the region and pose a risk for a giardiasis epidemic.  }, Keywords = {giardia , genotyping, Iran}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2150-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2150-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Abdi, Jahangir}, title = {Title: Genotyping of Fasciola spp Isolated from Domestic Animals Using PCR-RFLP Method in Western Iran}, abstract ={Objectives: The most common parasites responsible for fascioliasis are F. hepatica and F. gigantica. Fascioliasis is an important problem in terms of health and economics. The western part of Iran is one of the major hubs of animal husbandry and the prevalence of fascioliasis is high. The aim of Abstract  References  Citations  Supplementary Data  Genotyping of Fasciola hepatica Isolated from Domestic Animals in the West of Iran ADD TO CART BUY NOW Buy Article: $68.00 + tax (Refund Policy) 2 11/30/22, 3:06 PM Genotyping of Fasciola hepatica Isolated from Domestic Animals in...: Ingenta Connect https://www.ingentaconnect.com/content/ben/iddt/2019/00000019/00000004/art00011 2/2 the current study was to determine the Fasciola spp. present in the western part of Iran. In the present study, 45 samples were collected from slaughterhouses in three provinces in the western part of Iran, including Ilam, Lorestan and Kermanshah. Methods: The flukes were detected using morphological methods and the DNA of all samples was extracted. The ribosomal internal transcribed spacer (ITS1) was identified by PCR and PCR-RFLP techniques using the Rsa1 restriction enzyme. Then, 15% of the samples were sequenced. Results: Based on their ITS1 sequence, all samples showed 700 bp bands. The results of sequencing showed a similarity of 99% to 100% across samples. Using the Rsa1 restriction enzyme, all samples produced three distinct bands (60 bp, 100 bp, and 360 bp). These results demonstrated that the most common fasciola in the western part of Iran in sheep and cattle is F. hepatica. Conclusion: The results of the present study showed that only the species F. hepatica is parasitizing livestock in the western part of Iran. Further studies using new molecular markers for more accurate identification of fasciola-causing species will be useful in the control and prevention of fascioliasis.  }, Keywords = {Fasciola, genotyping, Iran}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2137-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2137-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Kikhavani, Sattar and pooyan, farahnaz}, title = {Comparison Polymorphism (5HTTLPR) SLC6A4 Gene In normal People and patients With severe Depression In Ilam State}, abstract ={Suicide and depression is a general and widespread problem among people. Worldwide, 16 deaths out of every 100,000 deaths are due to suicide. This statistic is more common in the southern regions of the world. It has also been estimated that the number of people who commit suicide is 10-40% more than those who commit suicide (1). The evidence shows that the personality and human behavior of Badgorgon is related to monoamine compounds, especially serotonin (2,3). Serotonin plays a key role as a neurotransmitter in the nervous system that controls many mental behaviors and physical actions of humans (sleep, sexual desire,...). When the neuron receives the signal, the serotonin stored in the vesicles is released into the synaptic space (input). In the next step, the serotonin in the synaptic space is connected to the receptors of the next neuron (postsynaptic neuron) and stimulates them. output) (4). Serotonin transporter gene (SLC6A4) encodes an integral membrane protein that is responsible for the transport of serotonin across synapses (5,6). The serotonin transporter molecule is very effective in the process of the effect of this vital substance, and if the concentration of this substance is low, serotonin is not transported in the synaptic space and accumulates there, and if the amount of this molecule is high, serotonin is transferred at a faster rate, and this causes Serotonin transmission may be unstable and less effective.}, Keywords = {Depression, serotonin, 5HTTLPR polymorphism}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2091-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2091-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Ghazanfari, Zeinab and esmaili, maryam and Mirzaei, Amin and Sayehmiri, Kourosh and Gholamiparizad, Eskandar and AbedzadehZavareh, Mohamad Sadegh}, title = {: The effect of Education to mothers based on health belief model on decreasing dental plaque index of 3-6 years old children of Ilam city in 2014.}, abstract ={: The effect of Education to mothers based on health belief model on decreasing dental plaque index of 3-6 years old children of Ilam city in 2014. : The effect of Education to mothers based on health belief model on decreasing dental plaque index of 3-6 years old: The effect of Education to mothers based on health belief model on decreasing dental plaque index of 3-6 years old children of Ilam city in 2014. : The effect of Education to mothers based on health belief model on decreasing dental plaque index of 3-6 years old children of Ilam city in 2014. : The effect of Education to mothers based on health belief model on decreasing dental plaque index of 3-6 years old children of Ilam city in 2014. children of Ilam city in 2014.  }, Keywords = {: The effect of Education to mothers based on, health belief model on decreasing dental, plaque index of 3-6 years old children of Ilam city in 2014.}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2283-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2283-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Ghazanfari, Zeinab and sohili, bahare}, title = {Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.}, abstract ={Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.Assessing the effect of education based on Theory of Planned Behavior (TPB) on delivery type  selection in pregnant women referring to Kermanshah health centers at 1393.}, Keywords = {Assessing the effect of education based on, Theory of Planned Behavior (TPB) on delivery ,type  selection in pregnant women referring to Kermanshah health centers at 1393.}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2282-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2282-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {valadbegi, hassan and Sadeghifard, Nourkhoda and Ghafourian, Sobhan and Mohamadi, Jasem and Nazari, Ali and Pakzad, Rez}, title = {Evaluation the status of patients with respiratory infections and preventive interventions taking antibiotics in these patients.}, abstract ={Overuse and inappropriate antibiotic prescription for acute respiratory infections (ARIs) are one of the major contributors to the current antibiotic resistance problem. Also, ARIs are one of the most common infections so that, they are of great importance and can play a very important role in mortality in children and adults due to their very widespread and rapid spread. So, the purpose of this study is to train physician communication skills with patients in order to reduce use of antibiotic and subsequently reduce antibiotic resistance, proper use of antibiotics in cases where it is necessary to use, reduce self-medication and ultimately reduce costs.  }, Keywords = {Prescribing antibiotics, Respiratory Infection, Intervention, Physician prescription}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2045-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2045-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {asadi, mahdieh and Taghinejad, Hami}, title = {Effects of education on knowledge, attitude and responsible environmental behavior of elementary school girls city of ilam in 1395}, abstract ={Background: Environmental awareness and understanding of environmental issues are influential variables in environmental behaviors, and it is imperative for the community to educate on human behavior. It is only in the light of this type of training that many resolved environmental crises and sustainable development are realized. The purpose of this study was to determine the effect of education on promoting environmentally responsible behaviors of first grade high school students in Ilam in 2016. Methods: This study was an empirical study that was done on female high school students in Ilam city in 2016. Data collection tool was a researcher-made questionnaire. Two girls' high schools were randomly selected from the first public high schools of Ilam and randomly assigned to the experimental (N= 165) and control (N= 165) groups. Educational intervention was designed and implemented in 5-sessions of 30-minutes including environmental concepts, waste production and recycling, air and water pollution, water and energy saving, sewage and disposal methods for the case group. One month after the intervention, students in both groups were evaluated. Data were analyzed with SPSS software using independent t-test, paired t-test, chi-square, correlation and regression. Results: Despite the similarity of the groups in the mean scores of knowledge, attitude and responsible behavior before intervention (P>0.05), there was a significant difference in the mean scores of all variables between the two groups after the intervention (P<0.05). Conclusion: Community education is an effective strategy to raise environmental information, Developing environmental sensitivity and beliefs and ultimately promoting responsible environmental behaviors among first grade female students.}, Keywords = {: Knowledge, Attitude, Health Education, Responsible Environmental Behavior, Secondary School, Girl student, Ilam}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1726-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1726-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Ghazanfari, Zeinab and Daneshvar, Samira and Aivazi, Ali-Ashraf}, title = {Effects of instruction on preventive behaviors of head lice infestation among female primary school children at Eyvan city in 2016}, abstract ={Abstract Background: Despite advances in health and medical education, head lice infestation as a common public health problem that is most prevalent in primary school children. The aim of this study was to evaluate the effect of health education program on preventive behaviors of head lice infestation among primary school girls at Eyvan city in 2016. Methods: This study was an experimental study which was conducted in 2016 on girl primary school students in Eyvan, Ilam, Iran. Data collection tools were a researcher-made questionnaire. Two girl primary schools were randomly selected from public primary schools and randomly allocated to case (N=95) group and control (N=62) group. Educational intervention was designed based health belief model in 5-sessions 30-mintues for the case group. One month after the intervention, the students in both groups were evaluated. Data was analyzed with SPSS vita independent t-test, pair t-test, X2, correlation and regression. Results: The two groups had no significant differences in the scores of knowledge, HBM constructs and preventive behavior before the intervention. But, after the intervention, the mean scores of all parameters significantly improved in the case group. Conclusion: Applying HBM can be an effective strategy to promote preventive behaviors against pediculosis among girl primary school students.  }, Keywords = {Keywords: head lice, health education, preventive behaviors, primary school}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1168-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1168-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Khorshidi, Ali and mansoorijalilian, marzieh}, title = {ٍEpidemiology of Road Traffic Injuries in Ilam Province in 2007-2012}, abstract ={Road traffic crashes (RTCs) are major public health challenges of world health systems, and the main lead‑ ing cause of death in children and young adults aged 5 to 29 years. This study aimed to assess the epidemiology of RTCs in Ilam, Iran.  }, Keywords = {Ilam, Injury, Epidemiology, traffic Road}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2243-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2243-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Tardeh, Samira and Tardeh, zeinab and Karimian, Mohammad and Sayehmiri, Kourosh}, title = {Study the Effectiveness of the Radiofrequency Ablation treatment for Varicose Veins: A Systematic Review and Meta-Analysis Study}, abstract ={}, Keywords = {Varicose Veins, Radiofrequency,Meta-Analysis}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-364-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-364-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Kafashian, Mohamadreza and Karimian, Mohammad and Kalvandi, Gholamreza and Ghaysouri, Abbas and Sadeghifard, Nourkhoda and Feizi, Jalil and Nazari, Ali and Kouhsari, Ebrahim and Kenarkoohi, Azra and Rahmati, Shoboo and Mozafari, Aliashraf and Ahmadi, Iraj}, title = {Establishing a hospital based clinical registry system for Coronaviruses Disease in mostafa Khomeini hospital, Ilam}, abstract ={}, Keywords = {2019 (Covid-19)}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-881-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-881-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {farokhi, roya and Khorshidi, Ali and abbasighahramanlo, abbas and Rostamkhani, Marzieh}, title = {Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) in the Elderly of Babol County in 1399 and classification of the Elderly by ADHD and accompanied disorders using Latent Class analysis}, abstract ={}, Keywords = {ADHD, LCA, ELDERLY, BABOL}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1233-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1233-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Moayeri, Ardeshir and GhasemiHamidabadi, Hatef and Darvishi, Marzieh}, title = {Transdifferentiation of the human umblical cord-derived mesenchymal stem cells to dopaminergic neuron on conductive hydrogel}, abstract ={Parkinson's disease (PD) is one of the most common disorders related to the destruction of the central nervous system, which affects almost one percent of people over 50 years old. Parkinson's disease is a neurodegenerative disease that results from the gradual loss of dopaminergic neurons in the substantia nigra of the midbrain. In the clinic, this disease is characterized by movement symptoms such as muscle stiffness, tremors at rest, slowness of movement and walking. Also, other symptoms such as impaired consciousness, memory and perception are also symptoms of Parkinson's Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) are one of the cells that have the potential to multiply and differentiate into other cells, including neurons (13,14). These cells can be used as an ideal source in regenerative processes due to easy access, rapid expansion in the culture medium and long-term survival in the host tissue. In addition, the mentioned cells have low immunogenicity, similar to bone marrow mesenchymal stem cells, and due to their low tumorigenic properties, they seem to be a suitable option for allogeneic transplantation. Therefore, in this study, this cell source is used for differentiation and production. Dopaminergic functional cell is used. In addition, other studies indicate that mesenchymal stem cells derived from the human umbilical cord have differentiating power towards fat, cartilage, bone and other cell lines and are also able to stimulate the nerve process through inducing substances. undergo transdifferentiation in invitro and in vivo environments and move towards nerve and glial cells}, Keywords = {Differentiation, Dopaminergic neurons, Human umbilical cord mesenchymal stem cells,}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2160-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2160-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Ahmadi, Iraj and Anvari, Enayat and Afifipour, Alireza and Fateh, Abolfazl and Asadi, Masoumeh}, title = {Evaluating the relationship between the rs12252 single nucleotide polymorphisms of Interferon-Induced Transmembrane Protein 3 (IFITM3) gene as host genetic factors in controlling COVID-19 infection}, abstract ={In the span of the COVID-19 pandemic, the number of deaths due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been increasing in a daily fashion. Morbidity and mortality among patients with or without comorbidities also suffering from COVID-19, demonstrates marked pattern variation. Such different patterns can be traced back to the genetic makeup of the host. Presently, single nucleotide polymorphisms (SNPs) found in the genetic framework of the host, can be used to assign therapeutic approach or characterise the prognosis of many different viral infections. One SNP of note is IFITM3, certain genotypes of which can predict disease severity. These SNPs have a determinant influence on the natural history of many viral infections. To date, the impact of these SNPs on the progression or control of the SARS-CoV-2 infection has not been studied in Iran. Specification of these SNPs in the Iranian population may introduce new means of viral infection control. Therefore, this study may provide the preliminary basis of the correlation between the genetic character of the host and viral infection.}, Keywords = {single nucleotide polymorphism, SNP, interferon-induced transmembrane protein 3, IFITM3, COVID-19, SARS-CoV-2}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1581-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1581-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {khoshnood, saeed and Sadeghifard, Nourkhoda and hydari, mohsen and moradi, melika and Iraqi, almas and irani, golnaz and Pakzad, Rez}, title = {Investigation of epidemiological features of brucellosis in Iran: A systematic review and meta-analysis study}, abstract ={Brucellosis occurs in all parts of the world except in areas where bovine brucellosis has been eradicated. Annually, 500,000 new cases are reported, mainly in the Mediterranean, Central Asia, the Arabian Peninsula, India and Latin America. Brucellosis is endemic in all parts of Iran and is still considered a health problem. Iran ranks fourth in the world with an average incidence of 24.43 per 100,000 people. Due to the long borders of the country and lack of supervision over the import of livestock, large number of nomadic population, traditional methods of animal husbandry, insufficient supervision over the production and distribution of dairy products and lack of regular vaccination and testing and killing of livestock, many cases have been reported.In studies conducted in different parts of Iran, the prevalence of brucellosis in Kazerun is 8.7%, Bushehr 8.10%, Kerman 2.3% 2.31%, Isfahan, Gilan (rural areas) 8.9%, Mazandaran 9.53% and all tribes in the country 5% were reported. Despite the importance of the disease and the different forms of the appearance of its signs and symptoms, a comprehensive study on the different signs and symptoms of the disease is not yet available. Therefore, this study was conducted in order to examine the different signs and symptoms of the disease in patients across the country in a structured review and to find out the frequency of each of these signs and symptoms in patients across the country. And letchr('39')s find a more general view of the manifestations of this disease of a thousand faces. This ultimately speeds up the diagnostic process and patients can achieve appropriate treatment in a shorter time}, Keywords = {Brucella, epidemiological features, meta-analysis}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1507-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1507-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Tardeh, Samira and Adibi, Amir and Mozafari, Ali Ashraf}, title = {Study the Prevalence of Suicidal Ideation and Suicidal Attempt during the COVID-19 pandemic: A Systematic Review and Meta-Analysis Study}, abstract ={Corona Virus 2019 (COVID-19) is a new infectious disease that emerged in late 2019 in Wuhan, China and spread rapidly around the world. The COVID-19 epidemic is seriously affecting the daily lives of people around the world, including their health, economic well-being and social interactions. An epidemic of infectious diseases, as a major stressors in the lives of people and people around, can have many effects on mental health. Unpredictability and uncertainty about the COVID-19 pandemic, fear of infection and COVID-19-related environmental changes are the main stressors that cause mental health problems. And some factors, including economic hardship, social support, increased stress, and unemployment, may be associated with suicidal behaviors. Suicidal behaviors are multifactorial and involve complex interactions between biological and environmental factors. Among them, a major risk factor for suicidal ideation is a stressful life. Preliminary reports of a suicide wave have been reported in several studies at different stages of the epidemic As a severe crisis, suicidal ideation and related factors in the general population must be systematically examined.}, Keywords = {Suicidal Ideation , Suicidal Attempt, COVID-19}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1530-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1530-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Shams, Morteza and Naserifar, Razi and Majidiani, Hamidrez}, title = {Determination of Toxoplasma gondii Tyrosine-rich oocyst wall protein by computer methods}, abstract ={Toxoplasmosis due to Toxoplasma gondii is a global threat with significant zoonosis. This parasite has two final hosts (cats) and intermediates (a wide range of warm-blooded animals). The most important complication of abortion parasites in pregnant women and domestic animals such as sheep and pigs, although in people with weakened immune system the disease occurs in the form of pneumonia (pneumonia) or brain (encephalitis). The parasite has three pathogenic forms for humans, each of which plays a major role in the epidemiology and transmission of the disease: oocysts (contaminated water and food), tachyzoites (congenital or through blood transfusions), and bradycosites (transmission through organ donation or meat products). (Infected with tissue cysts). More than 30 years have passed since the Toxoplasma vaccine study, but the commercial vaccine for humans has not yet reached the production stage. Killed or attenuated vaccines have not received much attention today in terms of human immunity or immunizing power in the body, but on the other hand, subunit vaccines are of interest to researchers. These vaccines include DNA vaccines or protein vaccines, which often work together with an adjuvant or helper to produce an appropriate immune response against the parasite. In this way, antigens from many different stages of the parasite's life have been identified and evaluated to assess immunization, including surface antigens (SAGs), and organ antigens in tachyzoites and brady zoites such as microns (MICs). , ROP (Dop) and Dense Granules (GRA). Since fewer studies have been performed on parasites related to the parasite oocyte wall, we decided to conduct the present bioinformatics study on Toxoplasma gondii oocyte tyrosine-rich antigen (TrOWP).  }, Keywords = {Toxoplasma gondii ,oocyst ,protein,Tyrosine}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1511-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1511-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {najafi, gelareh and Anvari, Enayat and Ahmadi, Iraj and Shahmir, Parasto}, title = {Evaluion of antibody titer of sinipharm and asterazenca vaccines in a cross-sectional study in ilam}, abstract ={Summary of the necessity of implementing the plan: Coronavirus disease 2019 (COVID-19), which causes serious respiratory illness, was first reported in Wuhan, the capital of Hubei, China. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a coated virus, belongs to the beta-coronavirus family and contains single-stranded RNA that has been identified as the causative agent of COVID-19. Vaccination is the most effective approach to control the rapid spread of the disease. Antibodies play an important role in creating immunity from vaccination. Numerous studies have shown an association between higher antibody titers and the development of immunity against pathogens. In this study, the immunogenicity and protective effect of Sinopharm and AsteraZeneca vaccines will be evaluated by measuring serum IgG titer against spike protein using Enzyme-Linked Immunosorbent Assay (ELISA), 21 days after the first and second doses. Forty healthy people, including 20 people receiving the Sinofarm vaccine and 20 people receiving the Astraznica vaccine, are taking part in the study. Alcohol and drug users, people with autoimmune diseases, malignancies, users of immunosuppressive drugs, and people with other underlying diseases will be excluded from the study. The study protocol will be conducted in accordance with the ethical principles of research in Ilam University of Medical Sciences. Serum IgG concentration against SARS-CoV-2 spike protein will be measured using the purchased kit. Polystyrene microtiter plates are coated with spike protein and serum samples (diluted 1: 100) and positive and negative controls are added to the plate wells in a total volume of 100 μl and the plates are heated to 37 ° C. They are incubated for 30 minutes. After five washing steps with washing buffer, 50 μl of TMB substrate solution and 50 μl of the corresponding buffer are added and the samples are incubated at 37 ° C for 10 minutes. The reaction was completed by adding 50 μl of 2 M sulfuric acid and the A450 would be measured.}, Keywords = {SARS-CoV-2 spike protein, Sinopharm, AsteraZeneca}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-1633-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-1633-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Moayeri, Ardeshir and Kafashian, Mohamadreza and Abbasi, Naser}, title = {Effects of diagnostic ultrasound wave on excitability threshold and electroshock induced apoptosis in Rat Hippocampal cells}, abstract ={Epilepsy is one of the most serious neurological disorders in the world, and its frequency is 1-2% in the world population, and more than 40 million people worldwide are suffering from it (1), and the possibility of its prevalence is different in every age, race, and social class. Also, taking into account that seizures are one of the most obvious symptoms of this disease, and according to the available documents in our country, the number of people with epilepsy in Iran is around 700,000 (2), so the relationship between seizures and disorders related to It should also be noted that from the anatomical point of view, the disease is associated with disturbances in the temporal lobe of the hippocampus and changes in the apoptosis process in the cells of the hippocampus. (3) From a functional point of view, it is one of the effects of seizures, that is, the effect on the ion channels in the cell. The aforementioned can be mentioned, and on the other hand, due to the increasing use of ultrasound waves in sonography and the therapeutic use of these waves, and the existence of numerous reports about its effects on ion channels and the excitability of cells, as well as the effects of these waves on the process of apoptosis. Various cells, the need for more research in the aforementioned field is quite tangible. Therefore, the purpose of this study is to investigate the effects of these waves in the diagnostic range of 3.5 MHz with an intensity of 65 mw/cm2 on the excitability threshold of nerve cells and also the effect of these waves on apoptosis induced by electroshock (as a proven teratogenic factor in intervention studies) E-applicable) in rat model.}, Keywords = {Ultrasound waves, seizures, apoptosis, hippocampus, pentylenetetrazole}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2162-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2162-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} } @article{ author = {Pakzad, Iraj and tahmasebi, zahra and asadollahi, parisa and sadeghikalani, behroz and Ghafourian, Sobhan and Sadeghifard, Nourkhoda and ghasemipashakalaei, esmail}, title = {Title: Study of Microbiological and drug resistance pattern of BAL (bronchoalveolar lavage) samples of patients Hospitalized of Imam Khomaini and Shahid Mostafa University Hospitals during one year}, abstract ={Background and purpose: Lung diseases are one of the common causes of premature death and annoying and serious ailments among people. Since the incidence rate of pneumonia and bacterial infection of the lower respiratory tract can be used as a criterion for evaluating the internal and interventional measures as well as the hospital infection control system, and considering that a study similar to ours has not been conducted in Ilam province, We found it necessary to conduct the present study. Materials and methods: BAL (bronchoalveolar lavage) samples were taken from hospitalized patients with respiratory problems by bronchoscopy. The samples were cultured on routine bacterial culture media, then their total cfu were counted and bacteria were identified. And antibiotic sensitivity was done by disc diffusion method according to CLSI protocol. PCR method using specific primers of 16srRNA gene for Mycoplasma pneumoniae, Chlamydia pneumoniae and mip gene for Legionella pneumophila was used to detect hard-to-grow bacteria. Chi square test and SPSS software were used for data analysis. In all cases, p values < 0.05) were considered significant. Results: Out of 44 BAL samples in patients by culture method, 100 isolates were detected, including: Staphylococcus aureus (24) 31.2%, Streptococcus group A (18) 23.4%, Enterococcus (11) 14.3%, Acinetobacter baumannii, Pseudomonas aeruginosa (11) 14.3%, Enterobacter (10) 13%, Micrococcus, Staphylococcus epidermidis and Klebsiella pneumoniae (5) 6.5%. And by PCR method (4 cases), 9.1% was positive for Chlamydia pneumoniae and no band was found for Mycoplasma pneumoniae and Legionella pneumophila. Acinetobacter showed the highest resistance of 81.8% to azetronam and ceftazidime. 75% of Staphylococcus aureus isolates resistant to cefoxitin (MRSA) and 83.3% had mec A gene, and resistance to vancomycin (VRE) was observed in 27.3% of enterococcus species. Resistance to piperacillin, cefotaxime, ciprofloxacin, and imipenem was seen in Pseudomonas aeruginosa isolates with a prevalence of 54.5%, 45.5%, and 36.4%. The frequency of organisms in the ICU department (46%) was higher than other departments. Discussion and conclusion: The presence of MRSA, Enterobacteriaceae resistant to third generation cephalosporins and Pseudomonas and Acinetobacter resistant to piperacillin, imipenem, cefotaxime, azetronam and ciprofloxacin among the studied departments and especially the ICU department are major concerns. For this reason, it is necessary to observe the principles of controlling infectious diseases of resistant bacteria.}, Keywords = {BAL, drug resistance, hospitalized patients, PCR}, volume = {5}, Number = {4}, pages = {0-0}, publisher = {}, url = {http://newresearch.medilam.ac.ir/article-1-2205-en.html}, eprint = {http://newresearch.medilam.ac.ir/article-1-2205-en.docx}, journal = {Technology and Research Information System}, issn = {}, eissn = {}, year = {2023} }