Reza Pakzad, Saber Soltani, Milad Zandi, Sara Akhavanrezayat, Zeinab Hosseini, Pooneh Malekifar, Iraj Pakzad, Habib Kakaei,
Volume 5, Issue 1 (6-2022)
Abstract
The ocular tropism of respiratory viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is reported, and studies showed ocular manifestations in coronavirus disease 2019 (COVID-19) patient. The aims of the current systematic review and meta-analysis study will be to determine the prevalence of ophthalmic manifestation in COVID-19 patients.
We will be searched the literature in Medline, Scopus, Web of Science, and Embase from December 1, 2019, until December 5, 2020, by using the main following MeSH keywords "SARS-CoV-2" and "ocular manifestations." The prevalence and 95% confidence interval (CI) will be calculated using binomial distribution and random effects. The meta-regression method will be utilized to investigate the factors affecting the heterogeneity.