Volume 1, Issue 1 (7-2018)
2018, 1(1): 0-0 |
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Ethics code: IR.MEDILAM.REC.1394.058
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Amraei M. The effect of hydroalcoholic extract of chickpea on the level of inflammatory markers in hypercholesterolemic rabbits. Journal title 2018; 1 (1)
URL: http://newresearch.medilam.ac.ir/article-1-280-en.html
URL: http://newresearch.medilam.ac.ir/article-1-280-en.html
Ilam University of Medical Sciences
Abstract: (2435 Views)
The results of the present study showed that administration of hydroalcoholic extract of chickpea in hypercholesterolemic rats caused a significant decrease in serum levels of triglycerides, cholesterol and LDL-c and a significant increase in serum levels of HDL-c. The extract also had the ability to reduce inflammatory factors so that its administration significantly reduced serum levels of IL-6, CRP, Fibrinogen and TNF-α in hypercholesterolemic rats. It is possible that the mechanism of this plant is due to the observed hypolipidemic and anti-inflammatory effects caused by its polyphenolic compounds. In addition, the results of the present study indicated that the protective effect of hydroalcoholic extract of chickpea is dose-dependent, as the highest effectiveness was observed at a dose of 75 mg / kg. According to the above, it can be concluded that the dose / kg 75 Hydroalcoholic extract of chickpea has the potential to be used as a natural product for the management of cardiovascular disease
: Cross sectional |
Subject:
General
Received: 2018/07/29 | Accepted: 2018/09/29 | Published: 2018/07/15
Received: 2018/07/29 | Accepted: 2018/09/29 | Published: 2018/07/15
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