Volume 4, Issue 3 (12-2021)                   2021, 4(3): 0-0 | Back to browse issues page

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Clinical Microbiology Research Center, Ilam University of Medical sciences, Ilam, Iran
Abstract:   (1203 Views)
Background and Aim: A close correlation are exist between asymptomatic oropharyngeal colonization of bacterial pathogens and a range of pediatric respiratory disease and if this pathogens contains the iron and virulence genes, person to person transmission and subsequent disease of this asymptomatic colonization, are a potential risk for children. Thus, in this study we evaluate the frequency of asymptomatic carriers of Streptococcus pneumoniae and Haemophilus influenzae in healthy children.
 
Material and Methods: In this study we assess the frequency of Streptococcus pneumoniae and Haemophilus influenzae in oropharynx and nazal cavity of 123 children from 2 to 6 of age in the kindergartens of ilam province by specific methods of culture and phenotypic diagnosis as well as PCR and Real-time PCR.
 
Results: The prevalence of asymptomatic colonization of Streptococcus pneumoniae and Haemophilus were 30/1 percent and 17/1 percent, respectively. Likewise a considerable relation was found between colonization of Streptococcus pneumoniae and Haemophilus influenzae in children that are resides in houseful and poor families.
 
Discussion and Conclusion: Asymptomatic colonization of pathogens such as Streptococcus pneumoniae and Haemophilus influenzae in the oropharynx in childhood, disrupt the unique homeostasis in Microbiota of this region and because of that respiratory microbiota, shaping the respiratory tract microbiota composition and consequent diseases in the future, thus   appointment of asymptomatic colonization of these bacteria in oropharynx of healthy children can be helpful for find ways to interfere with colonization of this pathogens or prevention of therefrom disease. Finally, this study can be used as a basis for further studies in the field of asymptomatic colonization of pathogenic bacteria in the oropharynx of healthy children to be used in the future.
 
Key Words: Asymptomatic colonization, children, oropharynx and nasal cavity, Streptococcus pneumoniae, Haemophilus influenzae, Real-time PCR.
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: Cross sectional |
Received: 2021/09/29 | Accepted: 2021/12/1 | Published: 2021/12/1

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